Presentation on Longhorn Vaccine & Diagnostics LLC PrimeStore® Suite of Products and Pipeline 1747 Citadel Plaza, Suite 206, San Antonio, Texas 78209 2 Bethesda Metro Center• Suite 905 • Bethesda, MD 20814 Phone: (210) 826-0910 Email: Info@lhnvd.com www.lhnvd.com
Issues with Specimen Collection Transport < 4 Days: 4˚C packs Laboratory testing Transport Medium: REMEL, Copan, BD or raw clinical specimen Sample pre-treatment Requires cold chain (4˚C packs or -70˚C dry ice) - $$$ Samples are viable and potentially infectious Shipment restrictions---hazardous materials and packaging, special handling - $$$ Quality control, i.e., temperature, transport monitoring documentation Stabilization/preservation of DNA/RNA from sample, short transport window > 4 Days: Dry Ice
PrimeStore® Molecular Transport Media Target: “From Sputum to Sequencing” No BSL3? No power? No cold chain? No timely specimen transportation? No Problem! PrimeStore® MTM, the Safe, Reliable, Accurate, Affordable Collection-to-Detection System “The Front-End for all Molecular Diagnostics”
PrimeStore MTM™ Advantages: Collect and transport at ambient temperature Ready for storage (in collection tube) Kills microbes, destroys nucleases (DNase/RNase) and stabilizes and preserves DNA/RNA Enhances nucleic acid testing sensitivity Compatible with silica-based extraction methodologies including spin columns and bead-based extraction kits
PrimeStore MTM™ Advantages: Compatible with multiple extraction kits/platforms Ambion, Qiagen (including robotic extraction) Roche MagnaPure and LightCycler Life Technologies 7000/7500 Others (i.e. BioMerieux, BioRad) Hain GenoType MTBDRplus Assay Facilitates POC detection or high throughput testing (fixed or mobile diagnostic laboratories)
“From Sputum to Sequencing” Swab in PS Transport Lab Safe, ambient temperature shipping Sputum Specimen Collection PrimeStore MTM Ion Torrent Laboratory Preparation Extraction PCR Sample processing