Kim Witmer Senior Vice President Chief Financial Officer Michael Nunn, Ph.D. Executive Director Research Development

Endocrinology Developmental Biology Neurobiology Metabolism Plant Biology Cognitive Neuroscience Chemical Biology Biophotonics Molecular Biology Cancer Aging Immunology Gene Therapy Stem Cells

 Founded by Jonas Salk in 1970  Designated as NCI Basic Center in 1973 Center includes 30 Faculty members 200 Post-doctoral researchers 50 Graduate research students  Cancer Center Director: Tony Hunter, Ph.D.  Cancer Center is distributed across Salk 62% of Institute investigators participate in Center programs

 Institutional: Philanthropy Revenue Diversification Cost Savings & Efficiencies  Research Development: Strategies Innovation Grant Program Advocacy

Operating Revenue by Source Note: Excludes subcontracts going out

 Increased direct support to Investigators Increased bridge funding Raised funds for 21 chairs for Cancer Center Investigators Provided Developmental chairs for 5 new Cancer Center members Found major donors to build new Core Resources Biophotonics, Next Gen Sequencing and Bioinformatics Target Cancer Center research in Capital Campaign

 Encourage Investigators to pursue all grant application options  Secured large foundation grant for multiple PI’s & Cores  Developed inter-institutional shared resources  Hired Director of Research Development

Major Administrative Costs Savings  Restructure Mailroom & Telecomm  Central Plant Upgrade – requires less maintenance  ARD – restructuring for efficiency  Procurement – savings  Worker’s Compensation Improvements  Renegotiation of Large Contracts

NIH applications, Awards and Success Rates

The office provides – 1.Stewardship and Coaching: Individual R01s Managing Change 2.Launching New Projects: Centers and Programs 3.Seed Funding 4.Advise Senior Leadership

Strategies for Success

1.The Right Opportunity 2.The Right Audience 3.Developing Agency Support Themes: Strategies for Success

Agency Websites: NIH Guide

Award Search: NIH RePORTER

The Right Opportunity Challenges for Cancer Research: Success Rates

The Right Opportunity Agency websites – become a pro: funding opportunities ✪ NIH ✪ NSF ✪ CDMRP ✪ Grants.gov funded projects ✪ NIH ✪ NSF ✪ CDMRP

Automated Funding Announcements: Agency or Commercial

The Right Audience Who will review your grant? This is ESSENTIAL information to have BEFORE you start writing …

Click on the grant number NIH RePORTER:

Study Section

Program Official

Developing Agency Support The best time to contact a Program Director? – BEFORE YOU START – required 6 weeks before submission of grants >$500K – NIDDK asks for 3-6 months notice for large programs Other Topics: Summary Statements Etiquette Negotiating an Award

The Research Development Office Leadership: Push vs. Pull Challenge for developing new projects and building teams Pull: –Investigator has a project and/or team already developed Push: –Outsider [President?, Chair?, Executive Director?] identifies collaborative research opportunities in line with faculty research interests

The Push –  Match opportunities to PIs: Find Leaders Collaborators – Identify experts (preferably local) to build a team  Sell the project: Know the competition – Identify similar funding Timing of Submission… use NIH RePORTER  P30 Program and External Advisory Board Meetings

Sample RDEV projects at the Salk Institute:  NCI Cancer Center Renewals in 2008 and 2013  Sanford Consortium: $43M facility award from CIRM  New Centers, complementing the CCSG  NINDS and NEI P30 awards …  CIRM Center of Excellence in Genomic Medicine

Salk Innovation Grant Program Established in 2006 with donor funding Average expenditures $1 million/year Awards up to $100K direct costs for one year Internal peer review with option for outside critiques 2 12 applications, 4 awards

Salk Innovation Grants: Leverage Major new projects seeded by SIG funding: $5 M Industry partnership program $2 M ARRA Grand Opportunities Award $4 M Foundation Award $4 M for two new NIH R01s

Cancer Center Pilot Grants Initiated in 2009 Uses NCI CCSG Developmental Funds Supports Cancer Focus: – Collaborations both intra- and inter-programmatic – Translational Research external, or using C3 resources (current RFA)

 Administrators can serve as liaison to leaders at Federal and State Agencies – NIH, CIRM, etc.  Administrators can join advocacy and lobbying groups – Association of Independent Research Institutes (AIRI) Example: Special Council Review of Well-Funded Investigators

H-index Analysis: Investigators from 4 Cancer Centers at AIRI Institutions

Analysis of NIH Competing Awards,

 Management ■ Human Resources ■ Infrastructure  Development  Portfolio Diversification  Unrestricted funds  Foundation & corporations  Grant Development  Seed Funding  Advocacy

 What is your state doing to support Cancer Research?  What management strategies have helped you conserve resources?  Are there alternative approaches to funding start-up projects?  Who you gonna call to change Federal or State policy?