 Cell Functions and Viral Lifecycles Topics in Human Pathophysiology Fall 2011 Gilead Drug Safety and Public Health.

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Presentation transcript:

 Cell Functions and Viral Lifecycles Topics in Human Pathophysiology Fall 2011 Gilead Drug Safety and Public Health

Outline  Enzymes  Organelles  Energy Production  DNA Replication  Protein Synthesis  Retrovirus Lifecycles

 Figure 2.23 Proteins in the cells have a variety of functions including structural proteins, and enzymes. Enzymes catalyze almost all cellular reactions “metabolism” Enzymes

Organelles

Energy Production by Cell Cellular Respiration Animation

Nucleus

DNA Structure

Replication Produces an exact copy of DNA Occurs prior to every cell division Transcription Converts a portion of double-stranded DNA to a single-stranded mRNA Occurs within the nucleus Translation Converts an mRNA code into one or more proteins Takes place in the cytoplasm DNA mRNA Protein Replication, Transcription, and Translation

Keys: = Cytosine = Adenine = Guanine = Thymine Parent strandNew (daughter) strands forming Parent strand a) The double-stranded DNA unwinds, and each single strand serves as a template for a new complementary strand. DNA Replication

Cell Division

Figure 3.33 Gene Expression

Figure 3.34b Transcription Animation Link

Figure 3.36 Translation Animation link

Figure 3.38

Figure 9.20 HIV virus

Retrovirus Lifecycle Animation Link

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