Institut für Kernchemie

Scientific profile of the Institute of Nuclear Chemistry and the research reactor TRIGA Mainz Chemistry / physics of the heaviest elements J.V. Kratz Fundamental research in nuclear chemistry J. V. Kratz Nuclear chemistry in life sciences F. Rösch Nucleon research J.V. Kratz, C. Plonka-Spehr Research reactor TRIGA Mainz G. Hampel Radio- pharmaceutical chemistry F. Rösch Spectroscopic methods T. Reich W. Nörtershäuser Speciation / analysis of the environment T. Reich G. Hampel Education and training

Ultratrace Analysis with Laser Radiation

Ultratrace analysis with RIMS Principal of the resonance laser ionization mass spectrometry (RIMS): 1. Production of an atomic beam 2. Efficient three step ionization of the atoms by lasers 3. Mass separation of the ions by a time-of-flight mass spectrometer 4. Extremely high isotopic selectivity of 5×10 12 and low experimental limit of detection of 10 6 atoms per sample

Plutonium in the environment –Powder sample from the Elbmarsch –Water sample from the North Sea and the Irish Sea – Incorporation measurements – Stolen plutonium from a reprocessing facility – Uranium amunitions from the Kosovo – Water samples from Rheinland-Pfalz Calcium-41 in the biological medicine Uranium-236 in the environment Applications of ultratrace analysis with RIMS

Application of synchrotron radiation for structural analysis Investigation of long-lived radio- nuclides (actinides) in –aqueous solutions, –soils, –plants and –microorganisms by X-ray absorption fine structure (XAFS) spectroscopy

Information from XAFS spectra Molecular symmetry and oxidation state

Information from XAFS spectra Bond distances and coordination numbers

The UNILAC- Accelerator A facility to produce artificial elements is installed at GSI- Darmstadt. Synthesis of artificial elements by nuclear fission

Island of stability in the N,Z diagram N

Periodic Table of the Elements (2008) 27 artificially produced elements Chemistry of the heaviest elements (transactinides)

Radiopharmaceutical chemistry Nuclear chemistry in life sciences Membrane receptors (Somatostatin): Diagnosis and therapy of neuro-endocrine tumors using 86/90 Y-labeled peptides Glycolysis: Visualization of glucose metabolism using 2-[ 18 F]FDG (2-[ 18 F]fluorodesoxy-glucose)

Brain research Synthesis of neurotransmitters Dopamine receptor system: Parkinson, Schizophrenia,... Opiate receptor system: Pain, addiction,... Glucose metabolisms: Alzheimer, epilepsy,... Benzodiazepine receptor system: Alcohol dependency, fear,…

Positron Emission Tomography (PET)

Reactor Training Course for the 2008 University of South Carolina TRIGA Mainz Dr. Gabriele Hampel Johannes Gutenberg - Universität Mainz