SCIENTIFIC PROGRAM OF THE CME COURSE TO BE HELD IN FLORENCE May 24 TH –May 25 TH 2010 GLOMERULAR DISEASES AND TRANSPLANTATION: SIMILARITIES IN PATHOGENETICAL.

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SCIENTIFIC PROGRAM OF THE CME COURSE TO BE HELD IN FLORENCE May 24 TH –May 25 TH 2010 GLOMERULAR DISEASES AND TRANSPLANTATION: SIMILARITIES IN PATHOGENETICAL MECHANISMS AND IN TREATMENT APPROACHES

May 24 th – Innate Immunity as trigger of renal damage. Focus on complement activation in glomerular diseases (Daha M) Activation of complement in humoral rejection (Regele H, Vienna) Discussion

Toll-like receptors activation and glomerular diseases (Anders JH) Role of dendritic cells in glomerular diseases and renal transplantation (Castellano G, Bari) Discussion B cells and antibody network in glomerular diseases ( Ronco P, Paris) B cells and antibody network in renal transplantation (Cozzi E) Discussion

May 25 th Therapeutical approaches to glomerular diseases and renal graft dysfunction NFkB and proteasome modulation of transcription factors in glomerular diseases and renal transplantation (Coppo R) 8, : Suppressors of Cytokine Signalling (SOCS): a new therapeutic target (Egido J) Growth factors: Biomarkers and therapeutic targets (Floege J) Discussion

9.40– 10.10Proliferation signal inhibitors in nephrology and renal transplantation ( Campistol J, Barcellona) 10.10– ° signal blockade in transplantation and renal diseases ( Grinyo J, Barcellona) Discussion Coffee break –12.00B cells inhibition in glomerular diseases (Jayne D, London) 12.00– 12.30B cells and antibody network inhibition in renal transplantation ( Salvadori M / Bertoni E, Florence) Discussion