Digestive system 1.Digestive system general feature 2.Oesophagus 3.Stomach 4.Large and small intestine 5.Liver 6.Pancreas.

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Presentation transcript:

Digestive system 1.Digestive system general feature 2.Oesophagus 3.Stomach 4.Large and small intestine 5.Liver 6.Pancreas

Digestive tube general structure

Digestive tube wall I. Mucosa: 1. Epithelium 2. Lamina propria 3. Muscularis mucosae II. Submucosa III. Muscularis externa IV. The outer tunica (adventitia or serosa)

Oesophagus

Stomach

Pyloric stomach

Small intestine

Villus-crypt system

Intestinal endocrine cell

Duodenum

Large intestine

Appendix

Rectum

Regeneration of epithelium

Liver Pancreas

Function of liver : 1. Syntesis: Bile Plasma proteine Plasma lypoproteines (vitamine K, D, E, A, cholesterine) 2. Detoxication 3. Destruction of spent red cell and reclamation of their constituens 4. Universal haemopoetic organ 5. Endocrine - somatomedine

LIVER & Pancreas LIVER Bile Hepatic artery Portal vein GI worm Hepatic veins Liver is the blood-processing glandular intermediary between you and your G-I worm (tract) that determines blood quality in two ways METABOLIC by Hepatocytes PROTECTIVE by Kupffer cells (M  s) W Beresford

Liver vasculature

Liver lobule

Liver specimen

Liver specimens

HEPATIC PARENCHYMA epithelial working tissue Plate of hepatocytes SINUSOID Plate of hepatocytes Endothelial cells Space SINUSOID Kupffer cell blood

CELL TYPES & ARRANGEMENT OF LIVER Microvilli Hepatocytes in plates Bile canaliculus SPACE OF DISSE Fenestrated Endothelial cells SINUSOIDKupffer cell STELLATE CELL HEPATOCYTE ENDOTHELIAL CELL KUPFFER CELL STELLLATE CELL

Hepatocyte, blood capilaries, bile canaliculus

Hepatocyte

bile canaliculus

Hepatocyte, blood capilaries, bile canaliculus

Schema of clasiccal and portal lobules and liver acinus

gallbladder

Epithelium of gallbladder

pancreas

Acinus and duct of pancreas

Homogenic and zymogenic zones

pancreatocyte

Langerhans islets

Classification of insulocytes: В- insulocytes – insulin А- insulocytes– glucagon D- insulocytes– somatostatin D 1 -insulocytes– VIP (vasoactive intestinal peptide) РР or F-insulocytes– pancreatic polypeptide