This article and any supplementary material should be cited as follows: Littman AJ, Thompson ML, Arterburn DE, Bouldin E, Haselkorn JK, Sangeorzan BJ,

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This article and any supplementary material should be cited as follows: Littman AJ, Thompson ML, Arterburn DE, Bouldin E, Haselkorn JK, Sangeorzan BJ, Boyko EJ. Lower-limb amputation and body weight changes in men. J Rehabil Res Dev. 2015;52(2):XX–XX. Slideshow Project DOI: /JRRD JSP Lower-limb amputation and body weight changes in men Alyson J. Littman, PhD; Mary Lou Thompson, PhD; David E. Arterburn, MD, MPH; Erin Bouldin, PhD; Jodie K. Haselkorn, MD; Bruce J. Sangeorzan, MD; Edward J. Boyko, MD

This article and any supplementary material should be cited as follows: Littman AJ, Thompson ML, Arterburn DE, Bouldin E, Haselkorn JK, Sangeorzan BJ, Boyko EJ. Lower-limb amputation and body weight changes in men. J Rehabil Res Dev. 2015;52(2):XX–XX. Slideshow Project DOI: /JRRD JSP Aim – Evaluate relationship between lower-limb amputation (LLA) and body weight change over 3 yr. – Examine extent to which weight change varies by level of amputation and body-mass index before surgery. Relevance – Excess body weight is a major concern for people with LLA, but little is known about relationship between LLA and subsequent changes in weight.

This article and any supplementary material should be cited as follows: Littman AJ, Thompson ML, Arterburn DE, Bouldin E, Haselkorn JK, Sangeorzan BJ, Boyko EJ. Lower-limb amputation and body weight changes in men. J Rehabil Res Dev. 2015;52(2):XX–XX. Slideshow Project DOI: /JRRD JSP Method Retrospective cohort study using clinical and administrative databases: – 759 males with amputation. – 3,790 nondisabled persons frequency-matched on age, body mass index, diabetes, and calendar year from 8 Pacific Northwest VA medical facilities. Estimated and compared longitudinal % weight change from baseline up to 39 mo of follow-up.

This article and any supplementary material should be cited as follows: Littman AJ, Thompson ML, Arterburn DE, Bouldin E, Haselkorn JK, Sangeorzan BJ, Boyko EJ. Lower-limb amputation and body weight changes in men. J Rehabil Res Dev. 2015;52(2):XX–XX. Slideshow Project DOI: /JRRD JSP Results Weight gain in the 2 yr after amputation was significantly more in: – Men with amputation than without. – Men with transtibial or transfemoral amputation (8%–9% increase) than in men with partial foot amputation (3%–6% increase). Generally, % weight gain peaked at 2 yr, followed by some weight loss in 3 rd year.

This article and any supplementary material should be cited as follows: Littman AJ, Thompson ML, Arterburn DE, Bouldin E, Haselkorn JK, Sangeorzan BJ, Boyko EJ. Lower-limb amputation and body weight changes in men. J Rehabil Res Dev. 2015;52(2):XX–XX. Slideshow Project DOI: /JRRD JSP Conclusion LLA is often followed by clinically important weight gain. Future studies are needed to: – Understand reasons for weight gain. – Identify intervention strategies to prevent excess weight gain and its deleterious consequences.