GeneGroupAnalysis 1.0.0-BetaCS Alejandro Quiroz-Zárate John Quackenbush lab

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GeneGroupAnalysis BetaCS Alejandro Quiroz-Zárate John Quackenbush lab

The “usual” analysis

The Key Idea This methodology was developed with Dr. John Quackenbush

GeneGroupAnalysis 1.2.0

Go to Example (real data set) – Gene expression from tumor samples 209 ER+ and 135 E- GEO reference accession numbers:GSE2034,GSE5327 – Affymetrix U133A – Conceive the data set with a Cross-Sectional Design – Question of interest: What are the biological mechanisms that drive the differences in Estrogen Receptor status?

Estrogen Targets Tissues

Estrogen and Cancer

Estrogen Receptors Trigger Gene Activation

Estrogen Receptor-Negative Breast Cancer

Analysis