Nanomedicines. Nanomedicines for diagnosis and therapy.

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Presentation transcript:

Nanomedicines

Nanomedicines for diagnosis and therapy

Materials for nano-medicines

Importance of nanomedicine for cancer treatments RES: An older term for the mononuclear phagocyte system - A part of the immune system that consists of the phagocytic cells located in reticular connective tissue. - The cells are primarily monocytes and macrophages, and they accumulate in lymph nodes and the spleen.

Nano-carriers for drug delivery

Liposomes

Advantages of liposome structure

Polysomes

Polymeric micells

Amphiphilic polymers for micells

Advantage of polymeric micells

Drug release from polymeric micells

Other types of polymeric micells

Dendrimers

Advantages of dendrimers

Hydrogel nanoparticles

Stealth effect of PEGs

Doxorubicine-EG-Folate modified micells

Doxorubicin

Liposome products

Angiogenesis in cancers

ERP (Enhanced permeability and retention) effect

Leaky blood vessels in tumors

Passive tumor targeting by EPR effect

Tumor targeting in nano-medicines

Barriers in in-vivo implementation

Lipid emulsion

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