GI Diseases Review 30 November :04 AM

Activated charcoal Antidote

Alosetron IBS treatment 5HT 3 receptor antagonist

Aluminum hydroxide Antiulcer Antacid

Amoxicillin Penicillin antibiotic Cell wall synthesis inhibitor Antiulcer Amino penicillin Inhibits peptidoglycan cross-linking

Ampicillin Penicillin antibiotic Cell wall synthesis inhibitor Amino penicillin Inhibits peptidoglycan cross-linking

Anthraquinones cascara segrada, danthron, senna Contact cathartics

Aprepitant dimenhydrinate Antiemetic Neurokinin 1 receptor antagonist

Atropine Anticholinergic Antimuscarinic Treatment for bradycardia, diarrhea, cholinesterase poisoning

Azithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

Balsalazide NSAID (salicylate) Treatment of IBD

Bisacodyl Contact cathartic

Bismuth subsalicylate Antiulcer Antidiarrheal

Budesonide Adrenocorticosteroid Glucocorticoid Anti-inflammatory steroid Inhaled OR treatment of IBD

Calcium carbonate Antiulcer Antacid

Cascara sagrada Contact cathartic Anthraquinone derivative

Castor Oil Contact cathartic

Cimetidine Antihistamine Antiulcer H 2 receptor antagonist

Cisapride Prokinetic agent 5HT 4 agonist

Clarithromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 50S ribosome Inhibits translocation

Danthron Contact cathartic Anthraquinone derivative

Dexamethasone Adrenocorticosteroid Glucocorticoid Antineoplastic Antiemetic Anti-inflammatory steroid Not by inhalation

Dimenhydrinate Antihistamine Antiemetic H 1 receptor antagonist

Diphenhydramine Classical antihistamine Antiemetic H 1 antagonist

Diphenoxylate docusate Antidiarrheal Opiate

Docusates Lubricating laxatives Stool softeners

Doxycycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Dronabinol Antiemetic Cannabinoid

Droperidol Antiemetic D 2 receptor antagonist

Erythromycin Macrolide antibiotic Bacteriostatic protein synthesis inhibitor 50S ribosome Inhibits translocation

Granisetron Antiemetic 5HT 3 receptor antagonist

Infliximab TNF inhibitor Anti-TNF monoclonal antibody Treatment of IBD

Ipecac Emetic

Kaolin Antidiarrheal

Lactulose Saline (osmotic) cathartic

Lansoprazole Antiulcer H + /K + ATPase inhibitor

Loperamide Antidiarrheal Opiate

Magnesium hydroxide Antiulcer Saline (osmotic) cathartic Antacid

Meclizine Antihistamine Antiemetic H 1 receptor antagonist

Mesalamine (5-ASA) NSAID (salicylate) Treatment of IBD

Methylcellulose Bulk laxative

Metoclopramide Prokinetic agent Antiemetic D 2 antagonist

Metronidazole Antibiotic Antiparasitic Antiulcer Anaerobes Reduction leads to intermediates that damage DNA

Mineral oil Lubricating laxative Stool softener

Minocycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Misoprostol Prostaglandin Antiulcer

Olsalazine NSAID (salicylate) Treatment of IBD

Omeprazole/esomeprazole Antiulcer H + /K + ATPase inhibitor

Ondansetron Antiemetic 5HT 3 receptor antagonist

Oxytetracycline Tetracycline antibiotic Bacteriostatic protein synthesis inhibitor 30S ribosome Prevents aminoacyl tRNA attachment

Pantoprazole Antiulcer H + /K + ATPase inhibitor

Pectin Antidiarrheal

Polyethylene glycol - electolyte solution Antidote Cathartic

Procarbazine Antineoplastic Miscellaneous Probably acts as alkylating agent

Prochlorperazine Antiemetic D 2 receptor antagonist Phenothiazine

Promethazine Classical antihistamine Antipsychotic Antiemetic H 1 antagonist

Rabeprazole Antiulcer H + /K + ATPase inhibitor

Ranitidine Antihistamine Antiulcer H 2 receptor antagonist

Rebamipide Antiulcer

Senna Contact cathartic Anthraquinone derivative

Scopolamine Anticholinergic Antiemetic Muscarinic receptor antagonist

Simethicone Anti-flatulent

Sodium bicarbonate Antiulcer Antidote Antacid Alkalinization of urine to treat drug toxicity (esp. barbiturates, salicylates, methanol)

Sodium phosphate Saline (osmotic) cathartic

Sucralfate Antiulcer

Sulfasalazine Disease modifying anti-rheumatic drug (DMARD) Metabolized to sulfonamide + salicylate (NSAID) Treatment of IBD

Tegaserod Antiemetic 5HT 4 receptor agonist

Tetracycline Antibiotic Bacteriostatic protein synthesis inhibitor Antiulcer 30S ribosome Prevents aminoacyl tRNA attachment