Lipid Metabolism By Amr S. Moustafa, M.D.; Ph.D..

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Presentation transcript:

Lipid Metabolism By Amr S. Moustafa, M.D.; Ph.D.

Structure of common Lipid classes

Overview of lipid digestion

lipid metabolism: Hormonal control

Lipid absorption: Mixed micelle

Secretion of Lipids from Entrocytes as Chylomicron

Chylomicron Metabolism

Triacylglycerol synthesis and degradation

Production of cytosolic acetyl CoA

Acetyl Co A carboxylase: Allosteric regulation

Acetyl Co A carboxylase: Covalent modification

De novo synthesis of palmitate

Malic enzyme: NADPH production

The relation between glucose metabolism and palmitate synthesis

Pathways for Glycerphosphate Production

Synthesis of Triacylglycerol Common Precursor For TG and PL Synthesis

Hormone-sensitive lipase: Hormonal regulation

Carnitine Shuttle

β-Oxidation of Fatty Acid

Propionyl CoA Metabolism

Phytanic acid

Ketogenesis

Ketolysis Ketogenesis

Structure of some glycerophospholipids

Sphingomyelin

Phosphatidylcholine synthesis

Intracellular Signaling by Inositol triphosphate

PI glycan membrane protein anchor

Phospholipases

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