Reza Sh. Kamrani M.D. TUMS 2 nd AOTrauma Hand Course Tehran IRAN 20, Apr. 2012
1- The importance of the bone healing knowledge 2- Physiology of bone healing 3- Interaction between bone healing and treatment 4- Bone healing in the hand
Bone has a remarkable capacity of healing The result of the treatment depends on the skill of the surgeon in taking the natural healing potential of the tissue Knowledge of bone healing helps the surgeon to better management of the fracture
A broken bone heals because......it is broken! Mr Alan Apley However it needs a favorable biological and mechanical environment
Bone healing classification; Enchondral ossification, Callus formation Direct osteonal healing. Non-callus Contact healing Gap healing Natural healing
Stages of healing 1- hematoma formation 2- inflammatory response 3- reparative phase 4- remodeling Fx. Healing is said to be complete when repopulation of the marrow space occure (months to years )
Hematoma Granulation T. Connective T. Fibrocartilage Mineralized cartilage Bone
Callus formation depends on Motion (direction) A good blood supply Füchtmeyer
Hente No bone
Abundant bone 10 cycles per day First stiffness then strength 5W Hente
Maintained instability leads to nonunion
Arrest of differentiation Good tissues—poor mechanics
Nonunion + Instability 0 Weeks
Nonunion + Stability = Healing 12 Weeks
Bone healing classification; Enchondral ossification, Callus formation Direct osteonal healing. Non-callus Contact healing Gap healing Treatment (stable fixation)
Lamellar bone formation: 1–2 μm/day
Remodelling occurs when the bone ends are in contact What happens if a small gap is present?
Invasion of blood vessels and cells
Bone deposition No cartilage tissue
Callus formation Resorption of fragment ends Interfragmentary cartilage
Variables affect on bone healing:
Injury variables Open fx. Severity of inj. Intra-articular fx. Segmental fx. Soft tissue interposition Damage of blood supply
Variables affect on bone healing: Injury variables Patient variables Diseas, Disorders Age Nutrition Systemic hormons Nicotin
Variables affect on bone healing: Injury variables Patient variables Tissue variables Type of the bone Bone necrosis Bone diseaseC
Variables affect on bone healing: Injury variables Patient variables Tissue variables Treatment variables Apposition of the frag. Loading & Micromotion Stabilization Soft tissue management
Variables affect on bone healing: Injury variables Patient variables Tissue variables Treatment variables Type of the bone Bone necrosis Bone diseaseC
Type of the bone Bones need rigid fix. Bones need no fixation
1- The importance of the bone healing knowledge 2- Physiology of bone healing 3- Interaction between bone healing and treatment 4- Bone healing in the hand
Team approach Bone biology Implant mechanics The surgeon The patient
AOTrauma Principles Course Bone healing and how it is influenced by treatment Erich Schneider, CH I would like to appriciate Dr. Schneider