Clinical Features.

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Idiopathic Thrombocytopenic Purpura
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Presentation transcript:

Clinical Features

Immune Thrombocytopenic Purpura Characterized by mucocutaneous bleeding and a low, often very low platelet count with otherwise normal peripheral blood cells and smears.

Immune Thrombocytopenic Purpura Clinical Features Patient Usually present: Ecchymoses and petechia. Thrombocytopenia May be present: Mucocutaneous bleeding (Oral/Nasal mucosa, gastrointestinal, or heavy menstrual bleeding) Rarely present: CNS hemorrhages may occur. Petechial rashes in the lower extremities (chief complaint) Platelet Count of 29 x 109/L (N.V. = 150-400 x 109/L) 1 episode of epistaxis which resolved with local pressure. Normal menstrual flow (4-5 days, 3-5 pads) None present

Immune Thrombocytopenic Purpura Characterized by low, often very low platelet count with otherwise normal peripheral blood cells and smears. Normal Values (Females) Patient’s Values Hgb: 120-160 g/L Hct: 0.36-0.48 WBC: 4.0 – 11.0 x 109/L Seg: 2.5-7.5 x 109/L Lympho: 1.5-3.5 x 109/L Mono: 0.2-0.8 x 109/L Platelet: 150-400 x x 109/L Hgb: 120 g/L Hct: 0.39 WBC: 12.0 x 109/L Seg: 0.60 (7.2 x 109/L) Lympho: 0.32 (3.8 x 109/L) Mono: 0.08 (0.7 x 109/L) Platelet: 29 x 109/L