AZƏRBAYCAN MİLLİ ELMLƏR AKADEMİYASI XƏBƏRLƏRİ ELM və İNNOVASİYA seriyasının İNNOVASİYA BÜLLETENİ № 9 UOD BİOMOLEKULLARDA QURULUŞ VƏ FUNKSİYA ƏLAQƏLƏRİ

PROJECT IDEA Project name: Structure-function relationships of biomolecules Proposal outline: Investigation of the conformational properties, molecular dynamics and electronic parameters, characterizing the spatial structure of biomolecules with important physiological functions using the methods of theoretical conformational analysis, molecular dynamics and quantum chemistry Project objectives: 1)to receive the knowledge about spatial structure of biomolecules, participating in many physiological processes occurring in living organisms 2) to explain on atomic-molecular level the mechanism of action of molecules 3) to offer theoretical modeling for the synthesis of the artificial analogs or medicines having specific functions Vilnius, 6-8 November, 2013

3WANTED Competences & Skills wanted: technical, design and coordination Types of partners sought: university and user-groups Work to be performed scientific: The modeling of the spatial structure of the biomolecules and the dissemination of received results

4 SKILLS OF THE PROPOSER Our skills: In our laboratory the universal program for the investigation of the spatial structure and of the structure-functional relationships of the biomolecules and molecular complexes have been prepared. With the help of this program and HyperChem, Chem Office, Gaussian 09,GAMESS, LEV, VEDA4 computer proqramms the spatial structure of the proteins, biopolymers, hormones and oligopeptides molecules and the enzyme- substrate and enzyme-ingibitor interaction effects were studied and results were published in scientific journals: J. Mol.Struct v.993, p , 2011, J. of Mol.Struct, v. 917, p , 2009, J. Mol. Struct., v.785, N 1-3, p.76-84, 2006, Journal of Protein and Peptide Lett., v.13, N 10, p.1- 9, 2006, Biophysics, v.50, N 1, p.5-12, 2005, Biophysics, vol.50, N 4, p , 2005, J.Mol. Struct, v. 688, p , 2004, Journal of Peptide Science, v.8, N 8, p , 2002, Studia biophysica, v.139, N 1, p.17-28, 1990, Journal of Peptide and Protein Res., v.27, N 2, p , 1986, Studia Biophysica, v.113, N 1-2, p.89-94, 1986 and other The received grants : 1) Internet Access and Training Program in Azerbaijan Founded by the Bureau of Educational and Cultural Affairs of the U.S. Department of State Administered by International Research and Exchange Board for the project: “Creation of website for coordination of scientists activities in the field of biophysics and other related disciplines such as ecologic, biotechnology and pharmacology 2) STCU project 3486: “Diffusion and ion-exchange processes in chalcogenide semiconductor nanoparticles, formed in volume of polymer matrix

5 CONTACTS Name: Godjayev Niftali Mehrali Institution/Organisation: Institute for Physical Problems, Baku State University ZIP & City: AZ-1148, Baku Country: Azerbaijan Phone number: (994-12)