December 7, 2011 How to Publish a Paper Lanny J. Rosenwasser, M.D. Dee Lyons/Missouri Endowed Chair in Immunology Research Professor of Pediatrics Allergy-Immunology Division Childrens Mercy Hospital Kansas City, Missouri Professor of Pediatrics, Medicine and Basic Science University of Missouri Kansas City School of Medicine

Disclosure Statement Lanny J. Rosenwasser, MD RESEARCH STUDIES Alcon, A-Z, GlaxoSmithKline, Genentech, Novartis MBBH/MacArthur Foundation, National Institutes of Health CONSULTANT Alcon,, A-Z, Genentech, GlaxoSmithKline, Novartis, Regeneron, Sanofi-Aventis SPEAKERS’ BUREAU Alcon, A-Z, Genentech, Novartis

Learning Objectives Understand the need for Publication of New Information Learn an Approach to Research, Clinical Research and Clinical Observation Nuts and Bolts of Publication.

Reasons to Publish A Paper Disseminate New Information Professional Advancement Personal Satisfaction

Professional Advancement Career and Academic Recognition Understanding and Learning Research and Communication Skills Required for Training, Job Placement or Promotions

Personal Satisfaction Completion of a Difficult Task Individual Recognition Acquiring Necessary Skills, Statistics Understanding the Literature Learning the Scientific Process

How to Get Started Know Your Interest Determine What You Can Do Mentors, Collaborators Define the Goals

Topics for Publications F I N E R F – Feasible I – Interesting and Important N – Novel E – Ethical R - Relevant

Protocol for a Research Project The Scientific Method Question and Hypothesis, Specific Aims Background and Significance Design and Methods Subjects Variables and Outcomes Statistical and Analysis – Results Discussion - Conclusion

Is the Scientific Paper a Fraud? Sir Peter Medawar, 1963 Hypothetico – Deductive Model vs. The Scientific Method

The Road to Publication Write the Manuscript Submit to a Journal Peer Reviews Complicated – revisions etc Acceptance/Rejection Edit Proof's and Galleys