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Hauser, R. The First-step study: a study to evaluate the effects of intitiating a fixed dose of Stalevo or levodopa/carbidopa t.i.d. in early PD patients requiring levodopa. Eur J Neurol 2006; 13(Suppl 2): 94. Jenner, P., Jackson M., Rose S. et al. Coadministration of levodopa/carbidopa/entacapone avoids dyskinesia induction in MPTP- treated primates with full or partial nigral lesions. Mov Disord 2006; 21 (Suppl 13): S73. Maratos, E. C., Jackson M. J., Pearce R. K. et al. Antiparkinsonian activity and dyskinesia risk of ropinirole and L-DOPA combination therapy in drug naive MPTP-lesioned common marmosets (Callithrix jacchus). Mov Disord 2001; 16(4): 631–641. Future directions I

Olanow, C. W. The STRIDE-PD (Stalevo Reduction In Dyskinesia Evaluation) Study: A Long-term, Controlled study to evaluate the effects of initiating Stalevo or carbidopa/levodopa in early PD. Eur J Neurol 2006; 13(Suppl 2): 93. Rascol, O., Brooks D. J., Korczyn A. D. et al. A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa. 056 Study Group. N Engl J Med 2000; 342(20): 1484–1491. Smith, L. A., Jackson M. J., Al-Barghouthy G. et al. Multiple small doses of levodopa plus entacapone produce continuous dopaminergic stimulation and reduce dyskinesia induction in MPTP-treated drug- naive primates. Mov Disord 2005; 20(3): 306–14. Future directions II