Toxicology Update Tracie Phillips, Ph.D. & Roberta Grant, Ph.D. Toxicology Division Texas Commission on Environmental Quality Environmental Trade Fair 2015

Objectives New Toxicology Database: Database Introduction Database Prototype Database Testing Updates to Odor Values: Odor Regulation Odor Changes Odor Timeline

T HE N EW T OXICOLOGY D ATABASE A new beginning NEW

What is the new database? Housed within the TAMIS database One stop shop: ESL List AMCV List Supporting documents

Why are we changing? Reduce errors Proper database structure More information/detail Dynamic Manual Spreadsheets 1000s of Chemicals Errors & Frustration

What will be different? 1. No more “Published List” spreadsheets

What will be different? 2. Information will be dynamic Database Updates New Info

What will be different? 3. ESL requests Consult the database 1 st No verification for existing values Database = Real Time At least a 2-week turnaround Each value documented Should be received early in the permitting process New ESL Request

What will be different? 4. All associated documentation will be linked: DSDs Fact sheets Public comments Interim documentation

What will be different? 5. Screening level reports Reports Toxicology Reports ESL Effects Screening Levels Summary Values Used in Permitting Only Detail All Values (Health & Welfare) AMCV Air Monitoring Comparison Values

What will be different? 6. More detail will be available: Each value will be dated

What will be different? 7. Source codes OdorInterim Long-termShort-term

What will be different? 8. List will be searchable by: Date Substance: CAS# Identified synonyms Substance type: Alcohols Surrogates

What will be different? 9. Use of surrogates: Promotes consistency Children Parent Chemical A Chemical X Chemical Z

What will be different? 10. Identified synonyms Styrene Phenyl- ethylene Vinyl benzene Styrene Monomer

What is the timeline? (4) Full Production – No More Published List: Date TBD (3) Transition & Beta Testing: Date TBD (2) External User Testing: Date TBD (1) Internal User Testing: Date TBD

P ROTOTYPE D EMO Time for a conceptual demonstration **For example purposes only, the following is not a true representation of the final product

TAMIS Welcome Screen

Login Screen

Report Selection Screen – Wizard Mode

Date Selection Screen

Report Parameter Criteria Screen

File Delimiter Selection Screen

Report Generation Screen

Report Output in Excel

T ESTING THE D ATABASE Testers Wanted!

External Testing If you would like to participate, send an to: Tracie Phillips: -or- Toxicology Division:

P ROPOSED C HANGES TO THE D ERIVATION OF O DOR -B ASED V ALUES A needed change NEW

Why do we regulate odors? Odor is a leading cause of citizen complaints The Texas Clean Air Act Intent is regulation of odor to prevent nuisance conditions, not odor detection

Why are we changing? Derivation with the intention of preventing odor nuisance conditions Large differences in reported odor threshold values Consistency – all odor values derived at one time

What will be different? Available and reliable studies Historical data Study bias considerations Source Data Malodorous chemicals Generic/surrogation, if needed Chemical Classification Identify all potential values Data integration to determine final value Derivation

What is the timeline? Odor White Paper Toxicity Factor Guidelines Update Odor Values Finalized

Contact Information Roberta Grant, Ph.D Tracie Phillips, Ph.D