Langerhans Cell Histiocytosis: Growth Hormone Treatment over 3 years in KIGS Simon J Howell KIGS 10 Year Book, 1999.

Slides:

Advertisements

Similar presentations

Adult Medical-Surgical Nursing

Advertisements

What is Endocrinology? The study of how the body is regulated by chemicals synthesized in one region of the body which then travel elsewhere in the body.

Physiology of endocrine system

09 Jan. 2013Endocrine-Glands.ppt1 Endocrine Glands.

Trends in the Diagnosis and Treatment of Short Stature as Revealed by KIGS Pierre Chatelain KIGS 10 Year Book, 1999.

The Endocrine System 8 Lesson 8.1: Functions and Control of the Endocrine System Lesson 8.2: Major Endocrine Organs Lesson 8.3: Endocrine Disorders and.

Terminology in Health Care and Public Health Settings Unit 7 Endocrine System.

Growth Hormone Treatment in Some Types of Skeletal Dysplasia and in Some Syndromes with Short Stature in KIGS Olcay Neyzi KIGS 10 Year Book, 1999.

Endocrine (Hormonal) System

Directions for Endocrine Take Home Quiz. 1. ADH 2. Growth Hormone (GH) 3. Oxytocin 4. TSH, T3, + T4 5. Epinephrine 6. PTH + Calcitonin 7. Prolactin 8.

Pituitary and hypothalamic diseases Dr.Malith Kumarasinghe MBBS( Colombo)

Hypopituitarism …and YOU! Your five minute look inside this disease of the anterior pituitary gland.

Copyright © 2012 The McGraw-Hill Companies, Inc. All rights reserved.McGraw-Hill PowerPoint to accompany Essentials of Medical Language 2e Allan, Lockyer.

© 2012 Delmar Cengage Learning. All Rights Reserved. May not be scanned, copied, duplicated, or posted to a publicly accessible website, in whole or in.

Major Endocrine Glands I. Hypothalamus II. Pituitary gland III. Thyroid gland IV. Parathyroid glands V. Pancreas VI. Adrenal glands VII. Gonads VIII. Pineal.

Copyright 2010 The McGraw-Hill Companies, Inc. Permission required for reproduction or display 10-1 PowerPoint to accompany Essentials of Medical Language.

MVG Katie Maude, Jasmine Stonacek, Juee Trivedi, Catherine Zhang.

Frequency of COP cells in control mice (caALK2) #1#2#3#4Average (%) Baseline (WT) undetectable Baseline (caALK2) 0.25 Day Day

Endocrine Physiology Bob Bing-You, MD, MEd, MBA Medical Director Maine Center for Endocrinology.

Precocious puberty Dr. Mahtab Ordooei. Precocious puberty Defined as the onset of secondary sexual characteristics before 8 yr age in girls and 9 yr in.

© 2010 Delmar, Cengage Learning 1 PowerPoint Presentation to Accompany.

The Endocrine System. Controls many body functions  exerts control by releasing special chemical substances into the blood called hormones  Hormones.

Hypothalamus Nicolette Cefai and Malia Bybee. Location In the brain below the thalamus.

Causes 1. Infarction : Sheehan’s syndrome 2. Iatrogenic : Radiation, urgery 3. Invasive : Large pituitary tumors CRANIOPHARYNGIOMA 4. Infiltration : Sarcoidosis,

MD.Trần Thị Bích Huyền Children hospital 1 Endocrine department

Pages  A control system of the body  By way of hormones (chemical messengers) that are released directly into the blood  Hormones control.

4.04 Understand the Functions and Disorders of the ENDOCRINE SYSTEM 4.04 Understand the functions and disorders of the endocrine system.

By Nathan Aleynick AP Biology Period 1 Ms. Straubel.

Copyright © 2004 Lippincott Williams & Wilkins Chapter 11 The Endocrine System: Glands and Hormones.

GH Treatment in Children in Remission from Leukaemia and Lymphoma in KIGS Nikolaus Stahnke KIGS 10 Year Book, 1999.

Growth Hormone Treatment in Children with Malignant Cranial Tumours in KIGS Michael B Ranke and David A Price KIGS 10 Year Book, 1999.

ANT. PITUITARY : ( UNDER INFLUENCE OF HYPTHALAMUS  RELEASING HORMONES ALL RELEASING HORMONES ARE STIMULATORY EXCEPT DOPMAMINE  INHIBITS PROLACTIN SOMATOSTAIN.

Chapter 9 The Endocrine System. Functions of Endocrine System  Second messenger system of the body  Uses chemical messages (hormones) that are released.

The Endocrine System Biology 12 Ms. Bowie.

Major Endocrine Organs

© 2017 Cengage Learning. All Rights Reserved. May not be scanned, copied or duplicated, or posted to a publicly accessible website, in whole or in part.

Hypothalmo-pituitary hormones By Dr.Mohamed Abd AlMoneim Attia.

Short Stature in Noonan Syndrome: Demography and Response to Growth Hormone Treatment in KIGS Barto J Otten KIGS 10 Year Book, 1999.

UK Renal Registry 16th Annual Report Figure Median height z-scores for transplant patients

Instructions for using this template. Remember this is Jeopardy, so where I have written “Answer” this is the prompt the students will see, and where.

Development of the KIGS Model for Predicting Growth Response to Growth Hormone Replacement Therapy in Children with Idiopathic Growth Hormone Deficiency.

Precocious puberty A case

Continuing the Treatment of Growth Hormone Deficiency During the Transition from Childhood into Adulthood Michael B Ranke and John P Monson KIGS 10 Year.

Growth Hormone Treatment in Children with Intrauterine Growth Retardation and Silver-Russell Syndrome Pierre Chatelain KIGS 10 Year Book, 1999.

Final Height Following Growth Hormone Treatment of Idiopathic Growth Hormone Deficiency in KIGS Wayne S Cutfield, Anders Lindberg, Pierre Chatelain, David.

Bio 449Lecture 13 - Endocrinology ISep. 29, 2010 Chemical messengers Classification of messengers Distance of travel Chemical structure Secreting tissue.

8 Lesson 8.1: Functions and Control of the Endocrine System Lesson 8.2: Major Endocrine Organs Lesson 8.3: Endocrine Disorders and Diseases The Endocrine.

Endocrine System HORMONES. Target Cells or Target Organs Specific tissue cells or organs affected by a given hormone. Classification of Hormones Steroids.

Endocrine System. Endocrine System: Overview Works with nervous system to coordinate activities Major influence on metabolism Endocrine glands: pituitary,

The Pituitary Gland 11(b). Overview of the Pituitary Gland The pituitary gland is located in the sella tursica ( Latin, “Turkish Horse Saddle” ) of.

Major Endocrine Organs Pituitary gland Thyroid gland Parathyroid glands Adrenal glands Pineal gland Thymus gland Pancreas Gonads (Ovaries and Testes) Hypothalamus.

Growth Hormone Treatment of Children with Prader-Willi Syndrome as Reported to KIGS: First-Year Growth Hormone E Martin Ritzén KIGS 10 Year Book, 1999.

Copyright © 2016, 2013, 2010 by Saunders, an imprint of Elsevier Inc. All rights reserved. Chapter 59 Drugs Related to Hypothalamic and Pituitary Function.

Aim: How does the endocrine system work to maintain homeostasis? Do Now: Explain how impulses travel from nerve cell to nerve cell.

ERT, estrogen replacement therapy

Pituitary Gland..

Figure 2 Top panel shows mean (SE) differences in near-final height (cm) (n = 71) in the AI, GH, and AI/GH groups regardless of length of treatment (n.

علم راهی بسوی آفریدگار جهان

Figure 1. Serum B-ALP levels in normal male (•) and female (○) children as a function of age. Serum B-ALP levels were increased during infancy and puberty.

Copyright © 2002 American Medical Association. All rights reserved.

Figure 1. Serum concentrations of IGF-I (A), IGF-II (B), IGFBP-3 (C), and ALS (D) throughout life in GHD (closed circles) and healthy control (open circles)

Unit 12: Human Regulation & Reproduction

מערכת הרבייה באדם ערכו וכתבו: אורית עמיאל-שרון והעיקר האהבה

DELAYED PUBERTY & HYPOGONADISM

Major Endocrine Glands Of The Endocrine System

Comparison between groups

Traumatic brain injury as a relevant cause of growth hormone deficiency in adults: A KIMS-based study Felipe F. Casanueva, MD, PhD, Alfonso Leal, MD,

Serum levels of antimüllerian hormone in early maturing girls before, during, and after suppression with GnRH agonist Casper P. Hagen, M.D., Kaspar Sørensen,

Increased frequency and number of KLL-specific clonotypes in tumors is associated with improved MCC-specific survival. Increased frequency and number of.

Presentation transcript:

Langerhans Cell Histiocytosis: Growth Hormone Treatment over 3 years in KIGS Simon J Howell KIGS 10 Year Book, 1999

S J Howell - KIGS 10 Year Book, 1999 Baseline characteristics of 82 KIGS patients with Langerhans cell histiocytosis TSH, thyroid-stimulating hormone; ACTH, adrenocorticotrophic hormone; LH, luteinising hormone; FSH, follicle-stimulating hormone; DI, diabetes insipidus

S J Howell - KIGS 10 Year Book, 1999 Response to GH treatment of patients with LCH (cross-sectional data for 3 years) (1/4)

S J Howell - KIGS 10 Year Book, 1999 Response to GH treatment of patients with LCH (cross-sectional data for 3 years) (2/4)

S J Howell - KIGS 10 Year Book, 1999 Response to GH treatment of patients with LCH (cross-sectional data for 3 years) (3/4)

S J Howell - KIGS 10 Year Book, 1999 Response to GH treatment of patients with LCH (cross-sectional data for 3 years) (4/4)

Response to GH treatment of patients with LCH (longitudinal data for 3 years) S J Howell - KIGS 10 Year Book, 1999 MPH, mid-parental height (1/4)

Response to GH treatment of patients with LCH (longitudinal data for 3 years) S J Howell - KIGS 10 Year Book, 1999 MPH, mid-parental height (2/4)

Response to GH treatment of patients with LCH (longitudinal data for 3 years) S J Howell - KIGS 10 Year Book, 1999 MPH, mid-parental height (3/4)

Response to GH treatment of patients with LCH (longitudinal data for 3 years) S J Howell - KIGS 10 Year Book, 1999 MPH, mid-parental height (4/4)

S J Howell - KIGS 10 Year Book, 1999 Response to GH replacement; comparison of patients with idiopathic GHD and with GHD associated with LCH n/a, not available (Ranke and Guilbaud 1991) (1/3)

S J Howell - KIGS 10 Year Book, 1999 n/a, not available (Ranke and Guilbaud 1991) Response to GH replacement; comparison of patients with idiopathic GHD and with GHD associated with LCH (2/3)

S J Howell - KIGS 10 Year Book, 1999 n/a, not available (Ranke and Guilbaud 1991) Response to GH replacement; comparison of patients with idiopathic GHD and with GHD associated with LCH (3/3)

S J Howell - KIGS 10 Year Book, 1999 a Corresponds to the start of the first year of GH treatment b GH doseand frequency of injections are median values based on the whole of the first year of GH therapy c The range quoted for pubertal patients in the cross-sectional group is the percentage who had entered puberty at the start and at the end of the first year d Data from only 76 patients e Data from only 15 patients Factors influencing first-year height velocity during GH therapy