Mbio 451–Immunology Dr. Ayman Mubarak

Lecture time : Sun Tue 9:00 -9:50 a.m. Credits : 3 hrs (2+1) Useful Online resourse: Course Information :

Recommended textbooks 1- Immunology. Kurby J et al (2002). 5 th Ed. Freeman. 2- Immune system. Parham P (2005). 2 nd Ed. Garland. 3-Immunology. Male D et al (2006). 7 th Ed. Mosby.

1- Molecules and cells involved in normal immune defense mechanisms 2- Organs of immune systems 3- Innate and adaptive immunity, 4- Humoral and cellular immunity structure/function relationships in antibodies antibody synthesis and genetic mechanisms for antibody diversity, 5- Molecular basis of T-cell activation, role of cytokines in adaptive immunity and inflammation. 6- Structure/function of B-cell and T-cell receptors and MHC-I and II. General description

7- Basis of acquired immune deficiency. 8- Hypersensitivity reaction, tolerance and autoimmunity General description

1- Introduction 2- Innate & Adaptive Immune response 3- Lymphoid Tissues 4- Complements 5- T-cell and B-cell function, receptors, activation and differentiation 6- Antibody structure and function Topics to be covered

7- Mucosal Immune system 8- Vaccine Immunology 9- Host response to infection 10- Hypersensitivity reaction 11- Application of Immunology Topics to be covered

CriteriaAssessment Assignment10 % Quizzes10 % Mid-term10 % Laboratory30 % Final exam 40 % Grading system Assignment deadline: 29/11/2015

Courtesy  Be Respectful  Pay Attention  If you can’t pay attention, at least keep it to yourself … don’t disrupt others.  Cell Phones off/silenced YAWN!