TASHKENT MEDICAL ACADEMY Department of Bioorganic and Biological Chemistry Bioorganic chemistry I COURSE SUBJECT : Alkaloids and Vitamins LECTURE №18 LECTURER.

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TASHKENT MEDICAL ACADEMY Department of Bioorganic and Biological Chemistry Bioorganic chemistry I COURSE SUBJECT : Alkaloids and Vitamins LECTURE №18 LECTURER : PROFESSOR A.D.DZHURAEV

PURPOSE OF LECTURES: Form of knowledge of the principles classification and structure important properties of alkaloids and vitamins as the chemical basis of for further orientation medicinal alkaloid nature and vitamins

The questions of: 1.Alkaloids 1.1. Alkaloids of pyridine and piperidine 1.2. Quinoline alkaloids group 1.3. Phenanthrene alkaloids - isoquinoline 1.4. Alkaloids of purine 1.5. Tropane alkaloids group 1.6. Isoquinoline alkaloids group 1.7. Indole alkaloids group 1.8. Alkaloids of Phenylethylamine

The questions of 2. Vitamins 2.1. Water-soluble vitamins Vitamin B1 (thiamine) Vitamin B2 (riboflavin) Vitamin B6 (adermin, pyridoxine) Vitamin B12 (antianemik, cyanocobalamin) Foul acid Vitamin C vitamin-like substance Para-aminobenzoic acid Vitamin B15 (pangamic acid) Inositol Lipoic acid.

Classification alkaloids 1. GROUP pyridine and piperidine 2. GROUP quinoline 3. GROUP phenanthrene - isoquinoline 4. GROUP Purina 5. GROUP tropane 6. GROUP isoquinoline 7. GROUP indole

Alkaloids pyrrolidine derivatives, pyridine, piperidine gigrin nicotine coniine tropane anabasine piperidine halkasi pyrrolidine halkasi

Tropane derivatives cocaineatropine

Piperidine derivatives piperine lobeline

Quinoline derivatives quinine morphine heroin

Isoquinoline derivatives papaverine codeine

CLASSIFICATION OF VITAMINS I. Water-soluble vitamins 1. Vitamin B1 (thiamine). 2. Vitamin B2 (riboflavin). 3. Vitamin B6 (adermin, pyridoxine). 4. Vitamin B12 (antianemik, cyanocobalamin). 5. Foul acid. 6. Vitamin C. II. Fat-soluble vitamins 1 Vitamin A 2. vitamin D 3. vitamin E 4. vitamin K 5. vitamin F III. vitamin-like substance 1. P-aminobenzyl acid. 2. Vitamin B15 (Pang acid). 3. Inositol. 4. Linden acid.

VITAMINS HCL salt of Vitamin B1 or Thiamin

Vitamin B2 or riboflavin

piridoksol pyridoxal pyridoxamine Vitamin В 6

Folic acid folic acid

ASCORBIC ACID tautomerism vitamin С Keto acid Gulon L - sorbose

vitamin-like substance p-aminobenzyl acid.

vitamin В 15 (pangamic acid)

Inosite

lipoic acid dihydrolipoic acid