Beginning of the chapter Heart health and genetics (Cardiovascular Sensor) 39.

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Presentation transcript:

Beginning of the chapter Heart health and genetics (Cardiovascular Sensor) 39

SENSORS CARDIOVASCULAR SENSOR Cholesterol/Triglycerides Homocysteine Arteriosclerosis Sudden cardiac arrest

SENSORS CARDIOVASCULAR SENSOR Predisposition to: 1)High LDL cholesterol 2)Low HDL cholesterol 1)Effect of omega-3 on HDL cholesterol 3)High triglycerides 4)High homocysteine 1)Vitamin B2 positively effects the homocysteine levels 5)Prolongation of the QT intervals 6)Effect of 26 drugs

22 genetic variations CARDIOVASCULAR DISEASES

Gene examples

CARDIOVASCULAR DISEASES Gene examples

CARDIOVASCULAR DISEASES Gene examples

CARDIOVASCULAR DISEASES Gene examples

CARDIOVASCULAR DISEASES Gene examples

CARDIOVASCULAR DISEASES Gene examples

CARDIOVASCULAR DISEASES Gene examples

CARDIOVASCULAR DISEASES Genetic predisposition

SENSORS CARDIOVASCULAR SENSOR Cardiovascular disease 1) Prevention 2) Early detection 3) Better treatment

CARDIOVASCULAR DISEASES Counselling example Prevention Regular exercises Do not smoke! As little alcohol as possible Low-fat diet Less animal, more plant foods Use vegetable oils Omega3 fish oil capsules have a negative impact on your cholesterol Early detection Regular medical blood tests Submit to a Resting ECG examination before taking QT altering medication

CARDIOVASCULAR DISEASES High risk, what to do now? Early detection Regular medical blood tests Regular QT interval tests Measure the electrolyte level when performing extreme sports

SENSORS CARDIOVASCULAR SENSOR Cardiovascular disease 1) Prevention 2) Early detection 3) Better treatment

PHARMACOGENETICS Various drugs and enzymes DRUG D 3A42C192E9 3A5 NAT2 DRUG C 2D6 DRUG B 2C9 DRUG A 1A2 break down

CARDIOVASCULAR DISEASES Optimal medication

CARDIOVASCULAR DISEASES Optimal medication

SENSORS CARDIOVASCULAR SENSOR Cardiovascular disease 1) Prevention 2) Early detection 3) Better treatment

End of the chapter Heart health and genetics (Cardiovascular Sensor) 39