Chapter 11 Cell Communication. Concept Check Questions Chapter 11 Cell Communication.

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Presentation transcript:

Chapter 11 Cell Communication

Concept Check Questions Chapter 11 Cell Communication

Explain how nerve cells provide examples of both local and long- distance signaling. Chapter 11 Cell Communication

Explain how nerve cells provide examples of both local and long- distance signaling. Synapse = local Electrical = long distance Chapter 11 Cell Communication

Nerve growth factor (NGF) is a water-soluble signal molecule. Would you expect the receptor for NGF to be intracellular or in the plasma membrane? Why? Chapter 11 Cell Communication

Nerve growth factor (NGF) is a water-soluble signal molecule. Would you expect the receptor for NGF to be intracellular or in the plasma membrane? Why? Hydrophylic Chapter 11 Cell Communication

What is a protein kinase, and what is its role in a signal transduction pathway? Chapter 11 Cell Communication

What is a protein kinase, and what is its role in a signal transduction pathway? A protein that phosphorylates another protein, often in a cascade. Chapter 11 Cell Communication

When a signal transduction pathway involves a phosphorylation cascade, how does the cell’s response get turned off? Chapter 11 Cell Communication

Protein kinase = on Protein phosphatase = off Chapter 11 Cell Communication

Upon activation of phospholipase C by ligand binding to a receptor, what effect does the IP 3 -gated calcium channel have on Ca 2+ concentration in the cytosol? Chapter 11 Cell Communication

Gate opens. Ca ++ flows out of ER. [Ca ++ ] goes up. Chapter 11 Cell Communication

How can a target cell’s response to a hormone be amplified more than a millionfold? Chapter 11 Cell Communication

How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

How can a target cell’s response to a hormone be amplified more than a millionfold? cascade Chapter 11 Cell Communication

Explain how two cells with different scaffolding proteins could behave differently in response to the same signaling molecule. Chapter 11 Cell Communication