Global Advocacy and TReND in Africa. Research training Research facilities Cost- effective model systems Open source Skills transfer programme Outreach.

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Presentation transcript:

Global Advocacy and TReND in Africa

Research training Research facilities Cost- effective model systems Open source Skills transfer programme Outreach

Research training Intensive practical-based schools: IBRO school on insect neuroscience and Drosophila neurogenetics (Uganda & Tanzania) – 4 th just finished TReND school on molecular biology of brain ageing (Mekelle, Ethiopia) – 1 st just finished TReND-ICIPE school on bio-informatics (Nairobi, Kenya) – Calls open, November 2014 TReND school on “How to build your own equipment with open source resources” (Addis Ababa, Ethiopia) – Planning for 2015 Human brain imaging and behavioural neuroscience course – being planned

Equipment donations paired with short visits from experts upon request from partner Universities Support research facilities and Skills transfer programme

Support research facilities and Skills transfer programme Important equipment donated so far to Universities in Uganda, Ethiopia, Tanzania and Nigeria

Optimising resources Use of cost-effective model organisms State-of-the-art genetics in Drosophila, Anopheles, Aedes Physiology methods in bees, grasshopers and crickets

Tom Baden Open Hardware Hardware

Science is expensive!

Open Source Software

Open Source Hardware! (partly)

Mini-“computers“ & microcontrollers ~$ ~$35 ~$30

Desktop 3D printers ~$2-4k ~$ RepRap Replicator2

Some open hacks for lab equipment Hackateria.org Sterilisation hood PCR Extracellular Amp Backyard brains

This is not a niche market! Pearce 2012, Science

Fully motorised micromanipulator

Pipettes

PhoneScope

Key: Customizabililty

Key: Customizabililty

Thingiverse – lots of free lab-designs

Survey amongst African academics Computer Literacy Never heard No access Have tried Routine user Open Hardware lowhigh N = 77 responses, 10 African countries, 23 Universities

Leveraging Open Hardware

Leveraging Open Hardware

Teaching how to improvise Chinese chop sticks Webcam

Teaching how to improvise Mobile phone camera ~10*9V Batteries in series to power the gel

Open Neuroscience A.M. Chagas

Some upcoming events University of Addis Abeba, Ethiopia Workshop “How to build your own lab- equipment“ A M Chagas and T Baden ICIPE, Nairobi, Kenya Workshop “Open Source tools in Bioinformatics“, Funding obtained! J Aleksic University of Addis Abeba, Ethiopia Workshop “How to build your own lab- equipment“, Grant submitted Crowdfunding campaign to establish a permanent 3D printing facility at Dar es Salaam International University P Parslow, L Prieto, T Baden et al.

Applications open now University of Dar es Salaam, Tanzania 3rd IBRO school on Insect neuroscience and Drosophila Neurogenetics. Aug 2014 T Baden, S Yusuf, F Stephano, L Prieto

Acknowledgements

Outreach Outreach to students and teach-the-teachers at primary and secondary schools as well as Universities and general public in Nigeria, Ghana, Uganda, and Tanzania Fight stigmas on brain diseases with education Mega-outreach during Brain Awareness week Press coverage – Nigerian National TV Attracted international funding – Wellcome Trust Run by TReND alumni using open source equipment

How?

Suggestions for effective brain research advocacy in Africa Governments Universities Industry -Campaign to raise sciences status -More funding for basic research -Promote IT literacy -Less teaching for researchers -Improve teaching methods- critical thinking -Encourage public outreach -More communication -Increase partnerships with university researchers -Train local technicians to maintain equipment

Summer schools We share 60% of our DNA 70% of known human disease genes have Drosophila counterparts. Inexpensive to bread Easy to transport Friendly community Genetic tools!!! Why flies?

Outcome 2011 Course survey (took into account for second course)

Outcome 2011 Course survey (took into account for second course)

Outcome 2011 Course survey (took into account for second course)

Neuroscience MSc course at KIU -Take the syllabus from Tuebingen University and adjust it to suit teaching capacity at KIU -Will be taught by local faculty when expertise is available, international faculty will fly in for short intensive courses, and on line teaching will be implemented to complement the teaching experience -Plan approved by the educational council in Uganda -In co-ordination with Tuebingen grad school for Neuroscience.