Symptom Distress During Breast Cancer Chemotherapy Does Race Matter? Margaret Quinn Rosenzweig, PhD, FNP-BC,AOCNP Associate Professor University of Pittsburgh.

Slides:

Advertisements

Similar presentations

†Source: U.S. Cancer Statistics Working Group. United States Cancer Statistics: 1999–2011 Incidence and Mortality Web-based Report. Atlanta (GA): Department.

Advertisements

Health Disparities: Breast Cancer in African AmericansIn Lansing Health Disparities: Breast Cancer in African Americans In Lansing Costellia Talley, PhD,

New England Journal of Medicine October 18;367: Relapse Risk after Discontinuation of Risperidone in Alzheimer’s disease Molly Moncrieff.

Targeted Cancer Therapeutics, LLC Investor Presentation.

® Introduction Low Back Pain and Physical Function Among Different Ethnicities Adelle A Safo, Sarah Holder DO, Sandra Burge PhD The University of Texas.

4.6 Assessment of Evaluation and Treatment 2013 Analytic Lung Cancer.

¡Celebremos La Salud!: A cancer prevention program for Hispanic and non-Hispanic White women living in a rural area Silvia Tejeda, MPH Doctoral Candidate.

Cancer Program Standards 2012: Ensuring Patient-Centered Care

In the name of Allah. Development and psychometric Testing of a new Instrument to Measure Affecting Factors on Women’s Behaviors to Breast Cancer Prevention:

Role of MRI in Breast Cancer Angela Kong Princess Margaret Hospital.

ASSESSING ADULT LEARNING PREFERENCE FOR SUCCESSFUL WOUND CARE IN A COMPREHENSIVE WOUND CENTER Ranjita Misra, PhD, CHES 1, Lynn Lambert, BS, CWS. CHT 3,

Breast Cancer Detection, Treatment, and Survival in Medicare and Medicaid Insured Patients Cathy J. Bradley, Ph.D. Professor of Health Administration Co-leader,

A STUDY OF RURAL CHILDHOOD OBESITY Dr. Marilyn Duran PhD, RN Department of Nursing Tarleton State University.

® Introduction Mental Health Predictors of Pain and Function in Patients with Chronic Low Back Pain Olivia D. Lara, K. Ashok Kumar MD FRCS Sandra Burge,

Click to edit Master subtitle style The Role of Attachment in brief group therapy for depression: An empirical study Dr Jo Wilson Professor Phil Richardson.

Knowledge, Cancer Fatalism and Spirituality as Predictors of Breast Cancer Screening Practices for African American and Caucasian Women Staci T. Anderson,

Breast Care for Women of Mid-Michigan (BCM) Mary Smania, MSN, FNP-BC Assistant Professor MSU College of Nursing Nurse Practitioner.

Mammography Screening Information for Providers Indian Health Service National GPRA Team.

Indianapolis Discovery Network for Dementia Forecasting the Future Impact of Early Detection and Management Program for Alzheimer.

Phase III Randomized, Placebo-Controlled, Double-Blind Study of Intravenous Calcium/Magnesium to Prevent Oxaliplatin- Induced Sensory Neurotoxicity, N08CB.

Finding N.E.M.O. Marvin R. Balaan, MD, FCCP System Division Director, Division of Pulmonary and Critical Care Medicine Allegheny Health Network, Pittsburgh.

Demonstration of a Process- Outcome Link for Smoking Cessation Melissa M. Farmer, PhD 1,2 Elizabeth M. Yano, PhD 1,2 Brian S. Mittman, PhD 1,2 Scott E.

® From Bad to Worse: Comorbidities and Chronic Lower Back Pain Margaret Cecere JD, Richard Young MD, Sandra Burge PhD The University of Texas Health Science.

Breast Cancer. What is this Disease? Second leading cause of cancer death in women Malignant (cancerous) tumor –Develops from cells in the breast that.

INCIDENCE AND SURVIVAL TRENDS OF COLORECTAL CANCER FROM 2002 TO 2011 BE Ansa; E Alema-Mensah; MD Claridy; JQ Sheats; B Fontenot, and SA Smith Georgia Regents.

Amany M. Shebl Professor Of Medical-surgical Nursing Dean. Nursing Faculty, Mansoura University, Egypt.

The Clinical Trials of HDC/ABMT in Women with Breast Cancer Prof Cindy Farquhar MD MPH University of Auckland, NZ.

Chronic Care Management Hypertension Results: Represents Health Disparities Collaborative for Hypertension Overall CAP Results.

“The African American Prostate Cancer Crisis in Numbers”

Colorectal Cancer Survivorship in Greene County, Pennsylvania: Assessment and Provider Education Mary Ann Ealy, Marlene Shaw and Carolyn Wissenbach Background.

Ethnic Differences in the Prognostic Value of Coronary Artery Calcification for All-Cause Mortality Khurram Nasir MD MPH, Leslee J. Shaw PhD, Sandy T.

Lipoatrophy and lipohypertrophy are independently associated with hypertension: the effect of lipoatrophy but not lipohypertrophy on hypertension is independent.

Do Instrumental Activities of Daily Living Predict Dementia at 1- and 2- Year Follow-Up? Findings from the Development of Screening Guidelines and Diagnostic.

MARQUETTE UNIVERSITY COLLEGE OF NURSING Perceived Cognitive Changes During Breast Cancer Chemotherapy Linda Piacentine, PhD, ACNP Jiannan Zhang, BSN, RN.

Quality of life results from a Phase III trial of trastuzumab plus chemotherapy in first-line HER2-positive advanced gastric and GE junction cancer Taroh.

Incorporating Multiple Evidence Sources for the Assessment of Breast Cancer Policies and Practices J. Jackson-Thompson, Gentry White, Missouri Cancer Registry,

Adjuvant Radiation is Not Associated with Improved Survival in Patients with Positive Margins Following Lobectomy for Stage I & II Non-Small Cell Lung.

Cooperative Agreement Number U58/CCU U58DP Spirit Health Education (S.H.E.) Circle Early Detection or Survivorship of Cancer in Underserved.

Breast cancer affects 1 in 8 women during their lives. 1 Population Statistics.

Efficacy of a “One-Shot” Computerized, Individualized Intervention to Increase Condom Use and Decrease STDs among Clinic Patients with Main Partners Diane.

Improving Cancer Outcomes in Camden Dr Lucia Grun 19 March 2014.

GEOGRAPHIC DISTRIBUTION OF BREAST CANCER IN MISSOURI, Faustine Williams, MS., MPH, Stephen Jeanetta, Ph.D. Department of Rural Sociology, Division.

Comparing and Validating Simple Measure of Patient-reported Peripheral Neuropathy for NCCTG Clinical Trials: a Pooled Analysis of 2440 Patients Heshan.

Janet H. Van Cleave PhD, RN1 Brian Egleston PhD2

Randomized Controlled CTN Trial of OROS-MPH + CBT in Adolescents with ADHD and Substance Use Disorders Paula Riggs, M.D., Theresa Winhusen, PhD., Jeff.

Symptom Severity, Attribution, & Preference for Assistance While Taking Chemotherapy or Targeted Agents Sandra Spoelstra, PhD, RN 1 ; Barbara Given, PhD,

Determining Preferences for Symptom Management Assistance For Those with Oral Anti-Cancer Treatment Sandra L. Spoelstra, PhD, RN GSA Annual Meeting New.

The Symptom Experience While Taking Oral Anti-Cancer Medication (Chemotherapy or Targeted Agents) S. Spoelstra, PhD, RN 1 ; B. Given, PhD, RN, FAAN 1 ;

BREAST CANCER BY STAGE OF DISEASE AT DIAGNOSIS, CENTRAL OKLAHOMA Arthur Owora, MPH; Aaron Wendelboe, PhD; David Thompson, PhD; Janis Campbell, PhD The.

Impact of Comorbidity on Chemotherapy Use and Outcomes in Solid Tumors: A Systematic Review Linda Lee, Winson Y. Cheung, Esther Atkinson, and Monika K.

Evaluation of the Community Patient Navigation Program within the Community Education and Outreach Initiative (CEOI) Patient Navigation is one strategy.

The Influence of Comorbidities on Use of Symptom Management Strategies in a Cancer Patient Intervention Gerontological Society of America November 19,

Should Elderly Patients Undergo Additional Surgery After Non-Curative Endoscopic Resection for Early Gastric Cancer? Long-Term Comparative Outcomes R3.

COLLABORATION WITH COMMUNITY PARTNERS TO PROVIDE BREAST AND CERVICAL CANCER SERVICES TO THE UNDERSERVED Patti Olusola, M.D. 1, Sarah Low, M.D. 1, Michelle.

Date of download: 9/20/2016 Copyright © 2016 American Medical Association. All rights reserved. From: Effects of a Palliative Care Intervention on Clinical.

Implementation of a lung health clinic in high-risk individuals in South East London: a prospective feasibility cohort study Background In 2013, lung cancer.

BREAST CANCER IN SETTING OF HIGH HIV PREVALENCE

Age and Racial/Ethnic Disparities in the Diagnosis of Breast Cancer in an Urban Population Joanne K. Fagan PhD, Denise Fyffe, PhD, Nadine Jenkins, CTR,

Figure 1. Raw mean scores of the MFI subscales ‘mental fatigue’ and ‘reduction in motivation’ (range 4–20, the higher the score the more mental fatigue.

Mild, moderate, and severe intensity cut-points for the Respiratory Distress Observation Scale©: A receiver operating characteristic curve analysis Margaret.

Treatment allocation bias

84 Breast Cancer patients

Evaluation of a Spiritually-based Intervention to Increase Colorectal Cancer Knowledge and Screening Among Church-attending African Americans and Whites.

Lung Cancer in Lewisham

Benefit of Early Palliative Care Intervention in End-Stage Liver Disease Patients Awaiting Liver Transplantation Alexandra J. Baumann, DO, David S. Wheeler,

M Javanbakht, S Guerry, LV Smith, P Kerndt

A single centre experience of febrile neutropenia rates in long acting compared with short acting GCSF preparations in breast cancer patients Dr Rebecca.

Gary Morse, Ph.D. Mary York, LMSW Nathan Dell, AM, LMSW

Receipt of Adjuvant Endometrial Cancer Treatment According to Race NRG Oncology/Gynecologic Oncology Group (GOG) 210 Study Ashley Felix, PhD, MPH Assistant.

Colorectal cancer survival disparities in California

Presentation transcript:

Symptom Distress During Breast Cancer Chemotherapy Does Race Matter? Margaret Quinn Rosenzweig, PhD, FNP-BC,AOCNP Associate Professor University of Pittsburgh School of Nursing Funding American Cancer Society, RSGT CPHPS Preliminary Work NCI-KO7 CA (03-08) Susan G. Komen Foundation, POP33008 Center for Research University of Pittsburgh School of Nursing

Background AA women have worse survival disparity than white women in breast cancer. Multifactorial: Environment, Patient and Provider –More under-dosing secondary to BMI or co-morbidities.

Under-Dosing? AA patients with cancer including AA women with breast cancer historically experience greater chemotherapy related symptom distress than white women. –Chemo is held, decreased or discontinued with symptom distress

Specific Aims 1.Determine the cumulative and individual symptom distress of women during breast cancer chemotherapy. 2. Compare the cumulative and individual symptom distress of women during breast cancer chemotherapy according to race.

Sample Starting January 1, December 31,2011 All AA women receiving chemotherapy with matched white sample. One urban cancer center with routine symptom assessment and distress screening.

Design Retrospective chart review Matched pair analysis Matched white women 1:1 for age and stage –Excel to SPSS v.20

Instrument The 9 item Edmonton Symptom Assessment Scale is used in routine clinic practice as a patient symptom reporting tool. Potential score is Higher scores indicate worse distress. The incidence and severity of symptoms were measured at baseline and each chemotherapy administration visit.

Total Chemotherapy Visits 240 visits for AA women –(mean 7.7 chemo visits/patient) 250 visits for W women – (mean 7.6 chemo visits/patient).

Mean Symptom Scores Total Mean ESAS Scores were worse during chemotherapy for AA than white women. Mean ScoresAA (n=28) White (n=28) P value At Baseline9.4/ /12.5p=.131 Total12.7/8.3/P=.001

Disparity in Specific Symptoms Total mean scores for 4 of the 9 symptoms over the course of chemotherapy. AAWhiteP value NauseaMean/SD 1.26/2.4 Mean/SD.4/1.4 P=.000 AppetiteMean/SD 1.14/2.2 Mean/SD.3/.9 P=.000 Shortness of BreathMean/SD.90/1.8 Mean/SD.24/.72 P=.000 FatigueMean/SD 3.2/3.2 Mean/SD 2.1/2.5 P=.000

Chemotherapy Dose Reduction White - 1/28 white patients dose reduced, no early cessation. African American - 1/28 patients dose reduced, 3/28 AA patients had early chemotherapy cessation

Conclusions Overall symptom distress and specific symptoms during breast cancer chemotherapy are worse for AA women than matched White controls. Clinical significance is unknown.

Conclusion This awareness can help nurses provide targeted anticipatory guidance and preventative measures in order to decrease symptom burden, and possibly prevent chemotherapy dose reduction and early treatment cessation.