JEFF CARMEN’S PASSIVE INFRARED HEMOENCEPHALOGRAPHY SYSTEM

HEG DISPLAY AND CONTROL UNIT

THRESHOLD SET AT 92.00, MOVIE HAS PAUSED

THRESHOLD SET AT 92.00, MOVIE IS PLAYING

HOW MANY SESSIONS DOES IT TAKE FOR MIGRAINES? 4 TO 6 SESSIONS TO HAVE AN IMPACT (TYPICAL) ANOTHER 10 OR 20 OR 30 OR MORE TO FINE TUNE THE PROCESS SESSIONS ARE PROGRESSIVELY SPREAD APART BASED ON SYMPTOMS

CASE SERIES pIR HEG HEADACHE TREATMENT SUMMARY FOR THE LAST 100 (relatively “clean”) MIGRAINES TREATED IN MY OFFICE

MALE (N=36) AVERAGE AGE:37.76 RANGE OF AGES: 8.21 TO DROPOUT BEFORE 6 TH SESSION: 8 (22%) IMPROVED IN 6 SESSIONS: 23 (64%) IMPROVED EVENTUALLY: 28 (78%) IF CONTINUED FOR AT LEAST 6 SESSIONS, IMPROVEMENT: 100%

FEMALE (N=64) AVERAGE AGE:34.74 RANGE OF AGES: 11 TO DROPOUT BEFORE 6 TH SESSION: 16 (25%) IMPROVED IN 6 SESSIONS: 38 (59%) IMPROVED EVENTUALLY: 44 (69%) IF CONTINUED FOR AT LEAST 6 SESSIONS, IMPROVEMENT: 92%

COMBINED MALE/FEMALE COMPLETING 6 OR MORE SESSIONS (76) CONTINUED FOR AT LEAST 6 SESSIONS: 76 IF CONTINUED FOR AT LEAST 6 SESSIONS, IMPROVED BY 6 TH SESSION: 61 OF 76 (80%) IF CONTINUED FOR AT LEAST 6 SESSIONS, IMPROVEMENT: 72 OF 76 (95%)IF CONTINUED FOR AT LEAST 6 SESSIONS, IMPROVEMENT: 72 OF 76 (95%)

HEADACHE IMAGES IN INFRARED HEAT OUTPUT COLOR CODE: BLACK IS COLD WHITE IS HOT RANGE: ABOUT 10 DEGREES (F) JUST NOTICABLE DIFFERENCE.1 DEGREE (F)

11YO, MALE PRE TREATMENT: PAIN INTENSITY: 8 to 10 DURATION: 1 month migraine (status) # SESSIONS: 7 POST TREATMENT: NO HEADACHES, 2 MONTH FOLLOW-UP (IMPROVEMENT AFTER FIRST SESSION)

11YO, MALE 12/13/01

11YO, MALE 8/26/02

11YO, FEMALE PRE TREATMENT: PAIN INTENSITY: 6 to 10 DURATION: 2 month, baseline 6, surge to 10, daily afternoon migraine # SESSIONS: 5 POST TREATMENT: NO HEADACHES, 2 MONTH FOLLOW-UP

11YO, FEMALE 5/16/02

11YO, FEMALE 7/15/02

15YO, MALE PRE TREATMENT: PAIN INTENSITY: 3 to 10 FREQUENCY: daily, mostly mornings, 3 months DURATION: 4 hours per migraine # SESSIONS: 9 POST TREATMENT: Not finished but stable, 10 per month, pain 0 to 5

15YO, MALE, 6/11/02 11:30am

15YO, MALE, 8/19/02, 8:10am

15YO, MALE, 7/26/02, 6:56am

15YO, MALE, 7/26/02, 7:58am

15YO, MALE, 8/12/02 8:26am, mild migraine

DISCUSSION OF CASE SERIES IMPROVEMENT IN MIGRAINE CORRELATES WITH INCREASED FRONTAL ACTIVITY MY BEST GUESS IS THAT THE MECHANISM HAS SOMETHING TO DO WITH INHIBITION AND TIGHTENING OF NEGATIVE FEEDBACK LOOPS

END OF “100 MIGRAINES”