INTRODUCTION

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This is not a LECTURE……………this is a discussion… sadly … not live !!! Objective is not to bombard information but to develop concepts…. So.. Get ready to chat !!

READTHINKUNDERSTANDREMEMBER VARIFY THAT YOU REMEMBER COMPLETELY NOW CLICK TO MOVE AHEAD TO NEXT STEP !!! GO SLOW !! Best luck !!!

SCIENCE OR DRUGS. PHARMACY PHARMACY Science about – Identification – Selection – Preservation – Standardization – Compounding & – Dispensing OF MEDICINAL SUBSTANCES !! PHARMACOLOGY PHARMACOLOGY Science about – Effect of drug on living animals, organs or tissues. About chemistry !! About chemistry fighting with biology!!

WHO DEFINITION OF “DRUG” READ ONLY ONE LINE…… THINK…… NOW REMEMBER….. MAKE SURE THAT YOU REMEMBER IN RIGHT WAY NOW MOVE TO NEXT LINE…

Vaccines are also drugs !! Conventional meaning of drug..chemical that cures!!! – Any substance or product… – That is used or intended to be used – To modify or explore physiological systems or – Pathological states – For the benefit of recipient. The one that is PRODUCED !! It can be naturally occurring like leaves of plant.. Molecules in research are also drugs !! Diagnostic dyes are also drugs !!

NEED A REVISION ?

Vaccines are also drugs !! Conventional meaning of drug..chemical that cures!!! – Any substance or product… – That is used or intended to be used – To modify or explore physiological systems or – Pathological states – For the benefit of recipient. The one that is PRODUCED !! It can be naturally occurring like leaves of plant.. Molecules in research are also drugs !! Diagnostic dyes are also drugs !!

Which means chemicals which… – Are vaccines… – Diagnostic agents administered to humans – Cures the diseases… – Relieves the symptoms – ARE ALL DRUGS NOW A FEW RELEVANT DEFINITIONS :

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PHARMACOGNOSY Science of the identification of drug To know

CLINICAL PHARMACY Involves cooperation of – Pharmacist with physician – In educating patient about – Complaince – And counseling him on how to take the medicine and – Monitoring errors in drug therapy. RELATED TO PHARMACIST & PATIENT !! RELATED TO DR. & PATIENT !!

PHARMACO KINETICS Movement of drug. Study of – Absorption – Distribution – Metabolism – Excretion of drugs. – “ What body does to the drug” – Also known popularly as “ADME” studies. DRUG MOVEMENT

PHARMACO DYNAMICS STUDY OF THE ACTION OF THE DRUG. Consequences of binding of drug with its target. Study of biological and therapeutic effects of drugs. “what drug does to the body” DYNAMO = POWER DRUG

THERAPEUTICS Deals with – Cure of the disease – Cure of the disease ( e.g. malaria,TB) – Relief of the symptoms – Relief of the symptoms. (e.g. fever,breathlessness) IT INVOLVES BOTH – Pharmacological treatment – Pharmacological treatment ( with drugs) – Non pharmacological treatment – Non pharmacological treatment (e.g. exercise, life style intervention, dietary modification, use of specific instrument or prosthesis for therapy)

NOW ITS TIME TO REVISE ……. WHAT IS – Drug – Pharmacy – Pharmacology – Clinical pharmacy – Pharmacokinetics – Pharmacodynamics – Therapeutics Answer to yourself !! If you don’t recollect, don’t move ahead, go back to 5 th slide.

QUANTITATIVE ASSESSMENT TOXICOLOGY Science of poisons which includes – Detection, – Measurement of poisons and – Treatment of poisoning. QUALITATIVE ASSESSMENT

CHEMOTHERAPY Effect of drugs upon microorganisms and parasites, living and multiplying in living organism and Treatment of cancers.

PHARMACOEPIDEMIOLOGY It is study of uses and effects of the drugs in large number of people.

PHARMACO-ECONOMICS It is analysis of the cost of the drug therapy to the healthcare system and the society.

PHARMACOVIGILANCE Process of – Identifying and – Responding to the issues of drug safety – Through the detection of drug effects usually adverse. “So it’s a science of keeping a watch on adverse reaction”. To keep watch !!

PHARMACOGENETICS Study of Inherited (genetically mediated) differences (variation) in Drug metabolism and response in humans.

PHARMACOGENOMICS Science that examines the – Heritable variation in genes that dictate the drug response of Humans Microbes & Tumors – And explores the ways these variations can be used to predict whether a patient will have Good response or Bad response or No response – Don’t hesitate to go for a revision if you are not comfortable !!!

PHARMACOPOEIA Is an official code containing A selected list of established drug and medicinal preparations With description of their Physical properties and tests for their – Identity – Purity & – Potency Examples : – Indian pharmacopoeia (IP), – British pharmacopoeia(BP), – US pharmacopoeia (USP) – European pharmacopoeia “So it’s a book describing chemical standards of drug” “So it’s a book describing chemical standards of drug”

NOW A TIME TO REVISION…. What is – Toxicology – Chemotherapy – Pharmacoepidemiology – Pharmacoeconomics – Pharmacovigilence – Pharmacogenetics – Pharmacogenomics – Pharmacopoeia Answer to yourself !! If you remember completely….its excellent ……………………… If you remember the concept but can’t remember WORD TO WORD, its ok….. If you don’t remember ………..its not as necessary as previous set !!!

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