Discussion Questions Discussion Questions 10/28/14 1. Using these words, please describe DNA Replication: semi-conservative, unzips, Helicase, DNA Polymerase, A, G, T, C double helix, hydrogen bonds. 2. When during the Cell Cycle does DNA replication take place ? Using your textbook or smart phone, please answer the following:

Reminders Eaves’ Second Period students, do not purchase a ticket for the play during school on Fri, You MUST be in class. Root Quiz next Monday, ……..STUDY!!! Exam on Tuesday, Read chapter 9, study your ppts and notes. Rough Draft of your Research plan is PAST due. The final, formal typed research plan (worth a double minor grade) will be due on 11/7/14 Start your science fair experiment Start working on your Science Fair Laboratory Composition Notebook. Follow the instructions in your Science Fair packet carefully. It tells you exactly what to do and how to do it. (Page 8)

QUIZ Clear your desks of everything Do NOT write on the quiz please Use CAPITAL letters please Keep your answers covered If you need to make up a quiz due to an absence… come see me Tues or Thurs during PLC Flip it over when you are finished and hang on to it.

9 week exam question 3

9 week exam question 4

Today’s Objective: Objective: DNA Mutations. How they occur and what the possible results of the mutations are.

DNA Mutations Fill in the blanks as we go through the ppt.

Don’t let this happen to you!!

MUTATIONS Changes in DNA that affect genetic information

What Causes Mutations? There are two ways in which DNA can become mutated: – Mutations can be inherited. Parent to child – Mutations can be acquired. Environmental damage Mistakes when DNA is copied

How are they inherited Only mutations to the gametes (egg and sperm cells) can be passed on to offspring. Mutations in body cells only affect the organism in which they occur. They cannot be passed on to offspring.

Significance of Mutations Most are neutral Eye color Birth marks Some are harmful Sickle Cell Anemia Down Syndrome Some are beneficial Sickle Cell Anemia to Malaria Immunity to HIV

Gene Mutations Point Mutations – changes in one or a few nucleotides – Substitution THE FAT CAT ATE THE RAT THE FAT HAT ATE THE RAT – Insertion THE FAT CAT ATE THE RAT THE FAT CAT XLW ATE THE RAT – Deletion THE FAT CAT ATE THE RAT THE FAT ATE THE RAT

Gene Mutations Frameshift Mutations – shifts the reading frame of the genetic message so that the protein may not be able to perform its function. –Insertion THE FAT CAT ATE THE RAT THE FAT HCA TAT ETH ERA T –Deletion THE FAT CAT ATE THE RAT TEF ATC ATA TET GER AT

Mitosis Foldable You need 2 sheets of one color You need one sheet of a different color You will use your power point notes to create a foldable similar to mine. Place your foldable in your science journal (it will be included in your journal grade)

Quick INFO

CSI Certification Practice

el/ el/ (Gel Electrophoresis simulation) 1 chrome book per table. Share with your group and work through the simulation together) wVoI

Exit Ticket 1. Describe the base pairing rules. 2. Compare and contrast purines and pyrimidines. 3. How do you think DNA replicates itself. YouTube DNA Replication YouTube Crash Course Mitosis

Exit Ticket 1. Please describe the cell cycle phases and substages. 2. When does DNA Replication occur? YouTube Crash Course Mitosis