The University of SydneyPage 1 Translational Research Closing the Gap Between Practice and Research Professor Tim Shaw Director Research in Implementation.

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Presentation transcript:

The University of SydneyPage 1 Translational Research Closing the Gap Between Practice and Research Professor Tim Shaw Director Research in Implementation Science and eHealth (RISe) Faculty, Health Sciences

What is Translational Research? 2 Applied research Basic research

Why Translational Research? Consistent evidence of failure to translate research findings into clinical practice 30-40% patients do not get treatments of proven effectiveness 20–25% patients get care that is not needed or potentially harmful (Runciman 2012; Grimshaw 2012; Schuster, McGlynn, Brook, 1998; Grol 2001)

Clinical & Translational Research: Valleys of Death Basic Biomedical and HSR Research Clinical Science & Knowledge Clinical Practice & Health Decision Making Translational Continuum – 17 years Valley 1 Valley 2 Copyright University of Pittsburgh 2006 Reis et al. Clin Transl Sci % enter into standard clinical practice; 1% lead to important health impacts Thanks to Eva Grunfeld

Translation DiscoveryTrials Implementation Improved Patient Outcomes T1T2 T3

Purposeful intent around an identified issue/priority What’s so special? Isn’t that what we have all being doing anyway?

Barriers

Silos Academia Hospitals Disciplines Geography QI Capacity and understanding

Eg Timelines Language End points Methodologies Rewards Different planets? Academia/IS QI/Practice

Lack of access to data

Enablers

Building capacity

New Partnerships and Funding Advanced Health Research and Translation Centres Translational Cancer Research Centres Academic Health Units

A systematic approach to identifying and closing evidence-practice gaps Longitudinal Programs Tim Shaw, Nicole Rankin, Sarah York, Phyllis Butow, Jane Phillips, Kate White, Jane Young, Puma Sundaresan, Sally Pearson, John Symes

Engaging MDTs in Translational Research High Performing Tumour Program

Paul Harnett, Lynleigh Evans, Henry Pleass, Guy Eslick, Arthur Richardson, Kim Hill, Kylie Museth, Anna Janssen, Tracy Robinson, Tim Shaw High Performing Tumour Program

Impact on clinical practice + Impact on professional development + Impact on quality improvement + Generation of research questions WS-LHD staff, Tim Shaw, Paul Harnett, Anna Janssen, Kylie Museth Data Innovation Lab High Performing Tumour Program

Disruptive technology 18