Left ventricle Michel Slama Amiens France
LV ventricle Ejection fraction Cardiac output Left ventricular filling pressure
Ejection fraction : systolic function, contractility?
Shortening Fraction of LV Area Ejection Fraction Systolic Function LEVEL 1
Mitral valve opening
NB Shiller, Heart, 1996;75:17-26 Estimated and measured EF LEVEL 1
Pouleur, Am J Cardiol, 1983;52: Influence of afterload on EF HT, AS Septic Shock
Cardiac output
How to perform echocardiographic examination in shocked patient? Cardiac output TTE: LEVEL 2
How to perform echocardiographic examination in shocked patient? Cardiac output TTE: LEVEL 2
Diastolic function
LV relaxation
Pathophysiology Pressure Normal Diastolic dysfunction Volume
LVEDP LVEDV 18 mmHg
Mitral flow : how to record ? Pulsed Doppler Correct Alignement Small window At the tip of mitral valve Visible opening sound Settings et filters 100 mm/s Average of 3 measurements
Early filling Late filling Vitesses LAP LVP Velocies P1 – P2 = 4 x V 2
LV Pressure Mitral flow
Type I of Appleton relaxation impairement Early diastole Late diastole Vitesses LAP LVP Velocities
Decreased preload SOHN, JACC 1997 BASETNT
Ea Aa DTI Mitral annulus Minimum settings Normal values Ea > 8 cm/s et Ea / Aa > 1 Ea = 15 ± 4 cm/s Aa = 10 ± 3 cm/s
Mitral annulus movement Ea AaEa Aa normal Ea = 18cm/s Ea > Aa Relaxation impairement (HT) Ea = 7,5cm/s et Ea < Aa
Left atrial size LAV = 0,5 x L1 x L2 x L3
Practical approach to assess diastolic function E’ lateral E’ Septal LA volume E’ lateral>10cm/s E’ Septal>8cm/s LA volume<34 ml/m² E’ lateral>10cm/s E’ Septal>8cm/s LA volume>34 ml/m² E’ lateral<10cm/s E’ Septal<8cm/s LA volume>34 ml/m² Normal left ventricular relaxation Athlet’s heart or constriction Left ventricular dysfunction
PAOP (Wedge pressure)
E (Mitral flow) depends on PAOP and on LV relaxation E’ (TDI mitral annulus) evaluate LV relaxation (preload independent) E/Ea ratio depends on PAOP LEVEL 2
E/E’ ratio predicts PAOP LEVEL 2
Combes A Int Care Med 2004 E/Ea ICU, mechanical ventilation LEVEL 2
Other tools to evaluate cardiac function Speckle tracking and strain evaluation 3D imaging assessement of EF MAPSE S wave on TDI at the mitral annulus
Septic shock
Myocardial infarction with cardiogenic shock
Pulmonary oedema
Congestive heart failure with pulmonary oedema
Unexplained shock
Conclusion