International perspectives on human gene editing: South Africa KEYMANTHRI MOODLEY DIRECTOR & PROFESSOR CENTRE FOR MEDICAL ETHICS & LAW DEPARTMENT OF MEDICINE.

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International perspectives on human gene editing: South Africa KEYMANTHRI MOODLEY DIRECTOR & PROFESSOR CENTRE FOR MEDICAL ETHICS & LAW DEPARTMENT OF MEDICINE FACULTY OF HEALTH SCIENCES STELLENBOSCH UNIVERSITY SOUTH AFRICA

South Africa Population +/- 52 million GDP $350 billion (US) 19.3% % on health % (Pakistan) Clinical trials +/- 2500

GINI COEFFICIENT 0.77

HIV Burden of Disease 6.8 million HIV positive new infections deaths 42% on ARVs

Justice & Equity Research & Capacity Development Cost of treatment Access to gene editing?

Public Engagement Vulnerable populations Science translation Informed Consent

Academy of Science of South Africa National Health Act National Health Research Ethics Council