Seborrheic Keratosis

Introduction The most common benign tumor in older individuals. Seborrheic keratoses have a variety of clinical appearance The etiology is not known. Seborrheic keratoses exhibit histologic evidence of proliferation. Increased cell replication has been demonstrated in seborrheic keratoses Can occur on almost any site of the body, with the exception of the palms and soles and mucous membranes.

Introduction/epidemiology Initially one or more sharply defined, light brown, flat lesions develop with a velvety to finely verrucous surface. They arise on normal skin. Their initial size is usually less than 1 cm, but the lesions can grow to several centimeters or more. Most common of benign skin tumors Usually multiple Rarely occur before the age of 30 years Slightly more common and more extensive in males Appear ‘stuck on the skin’ as if they can be removed by flicker of the fingernail Pathogenesis is unknown

Seborrheic Keratosis

SK

SK

Clinical features Evolves over months to years Present as oval, tan/light brown to black, slightly raised, sharply demarcated papules or plaques rarely more than 3cm Located mostly on the chest and back but also commonly affects the scalp, face, neck & extremities. Also in the inframammary region and genital lesions. However palms and soles are spared.

SK

Seborrheic keratosis are more common in sun exposed areas May arise from gene function mutations in FGFR3 &PI3K Six histologic variants:- hyperkeratotic, acanthotic, adenoid or reticulated, clonal, irritated and melanoacanthoma are seen

Treatment Easily removed by liquid nitrogen, curettage or combination of the two. Light freezing with liquid nitrogen alone is effective as is with simple curettage with local anaesthesia Light fulgration Shave removal

conclusion Discussed Benign and Malignant skin tumors Different types Treatment modalities

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What is this?