(3408983) 2.2 FC autism control FGR1OP2. (3806939) 1.4 FC autism control SMAD2.

Slides:

Advertisements

Similar presentations

10,000,000,000 cells 7,000,000,000 people 1984 Conservation of developmental mechanisms.

Advertisements

Peter Tsai Bioinformatics Institute, University of Auckland

P449. p450 Figure 15-1 p451 Figure 15-2 p453 Figure 15-2a p453.

Transcriptional profiling I – microarrays and proteomics

Supplementary Material Supplementary Tables Supplementary Table 1. Sequencing statistics for ChIP-seq samples. Supplementary Table 2. Pearson correlation.

LECTURE 2 Splicing graphs / Annoteted transcript expression estimation.

Ji-hye Choi August Introduction (2006) ABRF-NGS (the Association fo Biomolecular Resource Facilities next-generation sequencing study)

8.6 Gene Expression and Regulation TEKS 5C, 6C, 6D, 6E KEY CONCEPT Gene expression is carefully regulated in both prokaryotic and eukaryotic cells.

Primary Mets Node Patient 1Patient 2Patient 3 Primary Mets Node Patient 1Patient 2Patient 3 Primary Mets Node Patient 1Patient 2Patient 3 Primary Mets.

Supplementary Figure 2A. A. ZMYM6-variant missing Exon 2 C. ZMYM6-variant missing Exon 4 B. ZMYM6-variant missing Exon 5 D. ZMYM6-variant missing Exons.

Transcriptomics Sequencing. over view The transcriptome is the set of all RNA molecules, including mRNA, rRNA, tRNA, and other non coding RNA produced.

Figure SOM1. Functional roles of the genes affected in zmet2-m1 mutants. Although the genes localized on the intracellular membranes were slightly over-represented.

TEIN 4: RNA-seq analysis Akzam Saidin Sr. Bioinformatics Scientist.

Supplementary Fig. S1: GO classification of 2,318 differentially expressed genes during fruit ripening in tomato. The genes which show differential expression.

-1- Module 3: RNA-Seq Module 3 BAMView Introduction Recently, the use of new sequencing technologies (pyrosequencing, Illumina-Solexa) have produced large.

Supplementary Figure 1 List of top 50 most abundantly expressed lncRNAs and mRNAs in HP and PFC from RNAseq. Expression abundance of lncRNAs and mRNAs.

Supplementary figure 5.

Rupp et al. Supplementary Figure 1: Structure of the human troponin T gene Exon 6 Genomic DNA cDNA from mRNA mutation Exon 9 Exon bp Parts of genomic.

Figure S2 A B Log2 Fold Change (+/- cAMP) Transcriptome (9hr)

Additional file 8: Estimation of biological variations

Table 1: Efficiency for target genes

Supplementary Figure 2 Secondary transplanted brain tumors from PASC1 express human GH. Immuno-fluorescence staining of brain sections from mice implanted.

Sensitivity of RNA‐seq.

Bertram et al. (2005) , NEJM, 352: Bertram et al. (2005) , NEJM, 352:

Jacek Majewski The American Journal of Human Genetics

Gene-expression changes associated with stunting.

Comparative analysis of RNA and protein profiles.

Gene Sizes Vary Strachan p146 DYSTROPHIN.

Cross sectional comparisons of GAPDH and β-actin gene expression.

Copy-number alterations in an archival breast cancer sample.

Identification of genes associated with a gain of prion susceptibility Increased susceptibilities of revertant cell clones R2, R5 and R7 after retinoic.

y x y = x + 2 y = x + 4 y = x – 1 y = -x – 3 y = 2x y = ½x y = 3x + 1

Random Rectangles When given the cue turn the paper over. Within 5 seconds make a guess for the average area of the rectangles. When given the cue turn.

Analysis of total and polysomal RNA clk-1(qm30) and clk-1(qm30)+WT.

Supplementary Figure 4. Comparisons of MethyLight and gene expression data. PMR values (X-axis) were plotted against log2 gene expression values (Y-axis)

Mapping Whole-Transcriptome Splicing in Mouse Hematopoietic Stem Cells

Modeling Autism by SHANK Gene Mutations in Mice

Transcriptome changes in Cnot6l knockout oocytes and zygotes.

The transcript profiles in the three human cell lines based on RNA sequencing (RNA‐seq). The transcript profiles in the three human cell lines based on.

Figure 1 SpliceSeq “splice graphs” for the 7 qRT-PCR tested genes

Correlation of mouse gene expression with bacterial gene expression.

Phytochromes: Where to Start?

Individual genes exhibit distinct stage-specific expression among female gametocytes. Individual genes exhibit distinct stage-specific expression among.

Individual genes exhibit distinct female-enriched expression patterns.

Validation of RNA transcription profile differential expression using real-time quantitative PCR. Relative gene expression in cases compared with controls.

Correlation between DNA methylation and gene expression changes in T2D islets. Correlation between DNA methylation and gene expression changes in T2D islets.

Tripping the HCN Breaker

Transcriptomic and epigenetic changes associated with Factor 1 in the scMT data Transcriptomic and epigenetic changes associated with Factor 1 in the scMT.

NMDS clustering of sample types and differential expression analysis.

RNA-seq results at the SAM

Prachi Umbarkar et al. BTS 2019;j.jacbts

A typical current computational meta'omic pipeline to analyze and contrast microbial communities. A typical current computational meta'omic pipeline to.

CiCo relation to linear transcripts.

Correlation of DNMT3A expression and its variants with clinical parameters. Correlation of DNMT3A expression and its variants with clinical parameters.

Fig. 5 Correlation of RNA expression and protein abundance.

RT-PCR analysis of GFP splice variants in prp18a-1 mutants.

Which of the following expressions is the equation of the function {image} {applet}

Transition of the host cellular response over the course of ZIKV infection. Transition of the host cellular response over the course of ZIKV infection.

Gene expression signature of NK cells in NSG hL-7xhIL-15 humanized mice. Gene expression signature of NK cells in NSG hL-7xhIL-15 humanized mice. RNA sequencing.

Smad3-KO adipose tissues have increased FA uptake and β-oxidation.

Relative expression levels of three PTPN22 transcripts.

Trans-acting factors show enrichment of putative targets among differentially translated genes under DR. Trans-acting factors show enrichment of putative.

The endogenous IGRP gene is selectively expressed in βTC-3 cells and not in Y1 cells. βTC-3 RNA (50 μg) and Y1 RNA (50 μg) were annealed to labeled oligonucleotide.

Fig. 5 Transcriptional changes in dKO mice after HFD regimen.

The figure shows the graphs of {image} , {image} , {image}

SAF-1 expression in clinical breast cancer tissues.

Transcripts enriched and depleted in NB TICs compared with SKPs and other tumor tissues. Transcripts enriched and depleted in NB TICs compared with SKPs.

A and B, linearity of the preamplification step shown by a similar expression pattern of ERα mRNA in four breast tumor samples pre– and post–linear amplification.

Integrated analysis of gene expression and copy number alterations.

Retained introns in AA and EA cases.

Presentation transcript:

( ) 2.2 FC autism control FGR1OP2

( ) 1.4 FC autism control SMAD2

( ) 1.3 FC autism control PLA2G6

( ) 2 FC autism control ST7L

( ) 1.8 FC autism control KTN1

Supplementary Figure 4S. Examples of similar differentially expressed alternatively expressed genes in LCL (our study) compared with ASD brain samples. Differential alternative splicing of 212 genes has been recently identified in autism brain samples using high-throughput RNA sequencing (RNA-Seq) (Voineagu et al., 2011). We found differential exon expression for 78 of these genes in our autism group compared with controls (Supplementary Table 2A). Plots representing exon level expression for five genes whereby the same exon was differentially expressed in both LCL and autism brain samples are shown. Graphs were generated by Partek.Voineagu et