Teaching NeuroImages Neurology Resident and Fellow Section © 2014 American Academy of Neurology A 23 month old full term male with seizures.

Vignette A 23-month-old full term male presented with tonic-clonic seizures. CT (figure 1A) showed bifrontal parasagittal calcification. Lumbar puncture and routine lab tests were unremarkable. Brain MRI revealed corresponding signal abnormalities with gradient susceptibility (figure 1D) and enhancement (figure 1F). Differential diagnoses included prior infection, vascular malformation and tumor. Biopsy (see figure 2) was consistent with meningioangiomatosis (MA). Aw-Zoretic et al. © 2014 American Academy of Neurology

Imaging & Pathology Aw-Zoretic et al. © 2014 American Academy of Neurology

Imaging & Pathology Aw-Zoretic et al. © 2014 American Academy of Neurology

Meningioangiomatosis MA is a rare epileptogenic lesion involving the meninges and cortex characterized by vascular proliferation and calcifications. MA occurs sporadically or in association with neurofibromatosis 2 [1, 2]. Testing for NF2 proved positive in this patient, despite no other clinical stigmata. Aw-Zoretic et al. © 2014 American Academy of Neurology