SMOOTH MUSCLE Dr. Ayisha Qureshi MBBS, MPhil Assistant Professor.

Slides:



Advertisements
Similar presentations
Types of Muscle, structure and Function
Advertisements

Muscles and Muscle Tissue: Smooth Muscle Part C2 Prepared by Janice Meeking, W. Rose, and Jarvis Smith. Figures from Marieb & Hoehn 8 th ed. Portions copyright.
LECTURE 21 SMOOTH MUSCLE ANATOMY EXCIT. - CONT. - COUPL.
Smooth Muscle Excitation - Contraction
SMOOTH MUSCLES Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa.
Muscular System Chapter 8.
Chapter 8 Muscular System.
Muscle Tissue and Organization
Structure and action of skeletal muscle Mechanisms of contraction
Function depends on structure
Muscle Physiology Part II.
Make a short list of what you do voluntary and involuntary with your muscles… A. Def – organs composed of specialized cells that use chemical energy to.
ELAINE N. MARIEB EIGHTH EDITION 6 Copyright © 2006 Pearson Education, Inc., publishing as Benjamin Cummings PowerPoint ® Lecture Slide Presentation by.
MUSCLE PHYSIOLOGY Ass. Prof. Dr. Emre Hamurtekin EMU Faculty of Pharmacy.
Muscular System Chp. 6.
WINDSOR UNIVERSITY SCHOOL OF MEDICINE
The Muscular System. MUSCULAR SYSTEM Types of Muscle Tissue: Skeletal, Smooth, and Cardiac Skeletal, aka “striated” voluntary – attached to bones and.
Functions of the Muscular System 1.Produce body movements 2.Stabilize body positions 3.Regulate organ volume 4.Move substances within the body 5.Produce.
Contraction and Excitation of Smooth Muscle
Dr. Ayisha Qureshi MBBS, MPhil Assistant Professor
SMOOTH MUSCLES Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa.
The Muscular System What do skeletal muscles do? How do muscles work?
Physiology of Smooth Muscle
Contraction and Excitation of Smooth Muscles Arsalan Yousuf
MUSCLE CONTRACTION. Microscopic Anatomy of Skeletal Muscle Sarcomere Contractile unit of a muscle fiber Figure 6.3b.
صدق الله العظيم الاسراء اية 58. By Dr. Abdel Aziz M. Hussein Lecturer of Medical Physiology Member of American Society of Physiology.
Muscle Cells & Muscle Fiber Contractions
The Muscular System Skeletal muscle consists of numerous muscle cells called Muscle fibers. Muscle fiber terminology and characteristics Sarcolemma = plasma.
Muscle Physiology Chapter 7.
Cardiac Muscle Involuntary –heart only Contracts & relaxes continuously throughout life –Contracts without nervous stimulation! –A piece of cardiac muscle.
Muscle Types pgs Microscopic Anatomy of Skeletal Muscle pgs *emphasis will be placed on skeletal muscle.
Musculo-Skeletal Anatomy Making the body move!. Goals Important muscle groups to know Review muscle functions, types, and general anatomy In-depth look.
Smooth Muscle Unstriated muscle associated with visera. (Compare to skeletal muscle) Controlled by autonomic nervous system, hormones and paracrines. actin/myosin.
More About Cardiac and Smooth Muscle Tissue
Excitation and contraction of smooth muscle
MUSCLES.
They are specialised effectors that contract to cause movement
Unit Two: Membrane Physiology, Nerve, and Muscle
Dr. Abdelrahman Mustafa
Non-striated Muscle I. Locations of non-striated muscle in vertebrate body GI tract (including internal, but not external sphincters) Blood vessels and.
Kate Phelan Eleni Angelopoulos Anastasia Matkovski
Copyright © 2010 Pearson Education, Inc. Smooth muscle physiology  Organizational structure & function  Excitation contraction coupling.
U N I T II Textbook of Medical Physiology, 11th Edition GUYTON & HALL Copyright © 2006 by Elsevier, Inc. Chapter 8: Contraction and Excitation of Smooth.
COMPARISON OF SKELETAL & SMOOTH MUSCLE CONTRACTION:
Muscle Contractions By Jarad Settles Per. CD.
Muscle Tissue Muscle tissue functions – Movement – Maintain Posture – Joint stabilization – Heat generation (11.5a)
Muscular System Honors Anatomy & Physiology. Skeletal, Smooth, or Cardiac? SKELETAL Striated Voluntary Multinucleated Bound to bones to move skeleton.
Outline I. Types of Muscle II. Anatomy of Skeletal Muscle III. Sliding Filament Theory IV. Role of Ca+ in regulating muscle contraction.
Muscle Tissue & Skeletal Muscle Notes. Interesting Muscle Facts What is the biggest muscle in your body?
KEY CONCEPT Muscles are tissues that can contract, enabling movement.
The Muscular System. Muscle Tissues Cardiac –Involuntary striated muscle –Found only in heart –Smooth –Lines blood vessels, digestive organs, urinary.
MUSCLE SYSTEM Human Anatomy and Physiology. Muscle Tissue  The essential function of muscle is contraction  Three forms: cardiac, smooth, and skeletal.
MUSCLE AND NEURAL TISSUE. MUSCLE TISSUES – GENERAL CHARACTERISTICS 1.Composed of many cells 2.Well-vascularized 3.Muscle cells are elongated. Muscle cell.
The Muscular System What do skeletal muscles do? How do muscles work?                      
Section Sarcolemma- plasma membrane of a muscle fiber 2. Sarcoplasm- cytoplasm 3. Sarcoplasmic reticulum- smooth ER that stores Ca Myofibrils-
UNIT 7: MUSCULAR SYSTEM Chapter 9. GENERAL OVERVIEW: STRUCTURE –Hierarchy of skeletal muscles: muscle, fascicles, fibers, myofibrils, myofilaments –Coverings.
Myology Amanda Dunne. Learning outcomes By the end of the session you will be able to: Differentiate between the structure and function of the different.
How do muscle cells contract ?. What is the structure of a muscle fiber ? The sarcolemma, or plasma membrane contains invaginations called T (transverse)
Chapter 10 Muscle Tissue Muscle tissue functions Movement Posture
U N I T II Textbook of Medical Physiology, 11th Edition GUYTON & HALL Copyright © 2006 by Elsevier, Inc. Contraction and Excitation of Smooth Muscle.
Anatomy and Physiology Muscle Physiology Quiz Review
The Muscular System What do skeletal muscles do? How do muscles work?
Chapter 6 The Muscular System
DR. AYISHA QURESHI ASSISTANT PROFESSOR MBBS, MPhil
The Muscular System What do skeletal muscles do? How do muscles work?
Musculoskeletal System - Muscles
Dr.Mohammed Sharique Ahmed Quadri
Skeletal Cardiac Smooth
MUSCLES.
Muscles of the human body:
Presentation transcript:

SMOOTH MUSCLE Dr. Ayisha Qureshi MBBS, MPhil Assistant Professor

CLASSIFICATION OF SMOOTH MUSCLES UNITARY/ SINGLE UNIT/SYNCYTIAL/VISCERAL 1.Muscles of visceral organs.e.g. GIT, uterus, ureters & some of the smaller blood vessels. 2.Form a sheet or bundles of tissue. 3.Cell membranes show gap junctions that allows AP to pass rapidly from cell to cell. 4.AP spreads rapidly throughout the sheet of cells – cells contract as a single unit. MULTI-UNIT 1.Iris & Ciliary body of the eye, large arteries, Piloerector muscles 2.Showing discrete, individual smooth muscle fibers. 3.Smooth muscle cells not electrically linked. Each muscle fiber innervated by a single nerve ending. NT itself can spread and lead to an AP. 4.Selective activation of each muscle fiber that can then contract independently of each other.

Latch mechanism It is a state in which the dephosphrylated myosin remains attached to actin for prolonged period of time. This produces sustained contraction without consuming ATP & thus enables the smooth muscle to sustain long-term maintenance of tone without fatigue. E.g. urinary bladder full of urine.

COMPARISON OF SKELETAL & SMOOTH MUSCLE CONTRACTION:

S.NOCHARACTERISTICSSKELETAL MUSCLESMOOTH MUSCLE 1.LocationAttached to the skeleton Blood vessels, hollow organs, eye 2.Mechanism of contractionSliding filament 3.Nerve supplyMotor neuronsAutonomic nervous system 4.Level of controlUnder Voluntary control Under Involuntary control 5.Presence of Thick & Thin filaments Yes 6.Presence of TropomyosinYes 7.Presence of TroponinYesNo 8.Presence of T-tubulesYesNo 9.Level of development of Sarcoplasmic Reticulum Well DevelopedPoorly Developed

S.noCHARACTERISTICSSKELETAL MUSCLESMOOTH MUSCLE 10.Source of CalciumSarcoplasmic Reticulum (SR)ECF & SR 11.Overlap of Actin & MyosinOverlap of actin & myosin seen only in part of the A- band Continuous overlap of actin & myosin, b/c of side-polar cross bridges 12.ATP used directly by contractile apparatus Yes 13.Myosin ATPase activity; speed of contraction Fast or slow depending on type of fiber Very slow 14.Site of Calcium regulationTroponin in thin filamentsMyosin in thick filaments 15.Mechanism of Calcium action Physically repositions troponin-tropomyosin complex to uncover actin cross-bridge binding site Chemically brings about phosphorylation of myosin cross bridges so they can bind with actin

S.noCHARACTERISTICSSKELETAL MUSCLESMOOTH MSUCLE 16.Duration of contraction msecUpto 5 sec 17.Presence of Gap junctionsNoYes 18.Latch mechanismNoYes 19.NMJYesNo 20.NeurotransmitterAch onlyAch & Norepinephrine