Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial Featured Article: TODAY Study Group* Diabetes Care Volume 36: 1772-1774.

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Presentation transcript:

Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial Featured Article: TODAY Study Group* Diabetes Care Volume 36: June, 2013

STUDY OBJECTIVE To determine the prevalence of retinopathy in 517 youth with type 2 diabetes of 2–8 years’ duration enrolled in the TODAY study TODAY Study Group* Diabetes Care 2013;36:

STUDY DESIGN AND METHODS Retinal photographs were graded centrally for retinopathy using established standards TODAY Study Group* Diabetes Care 2013;36:

RESULTS Retinopathy was identified in 13.7% of subjects Prevalence increased with age, diabetes duration, and mean HbA1c Subjects in the highest BMI tertile had the lowest prevalence of retinopathy TODAY Study Group* Diabetes Care 2013;36:

CONCLUSIONS Prevalence of retinopathy and its association with HbA1c and diabetes duration is similar to that in youth with type 1 diabetes and adults with type 2 diabetes of known duration Mechanism underlying the reduced risk of retinopathy in the most obese individuals is unknown Follow-up of this cohort will help define the natural history of retinopathy in type 2 diabetic youth TODAY Study Group* Diabetes Care 2013;36: