Review Classification of CT – CT “Proper” – Supporting CT – Fluid CT
Bone (osseous) CT
– Cells
Bone (osseous) CT – Cells Osteoprogenitor cell
Bone (osseous) CT – Cells Osteoprogenitor cell (stem cell)
Bone (osseous) CT – Cells Osteoprogenitor cell (stem cell) Osteoblasts
Bone (osseous) CT – Cells Osteoprogenitor cell (stem cell) Osteoblasts Osteocytes
Bone (osseous) CT – Cells Osteoprogenitor cell (stem cell) Osteoblasts Osteocytes (in lacunae)
Bone (osseous) CT – Cells Osteoprogenitor cell (stem cell) Osteoblasts Osteocytes (in lacunae) Osteoclasts
Bone (osseous) CT – Cells Osteoprogenitor cells (stem cells) Osteoblasts Osteocytes (in lacunae) Osteoclasts – Matrix
– Matrix: arranged as lamellae
Collagen fibers
– Matrix: arranged as lamellae Collagen fibers Calcium phosphate salts
– Matrix: arranged as lamellae Collagen fibers Calcium phosphate salts (as hydroxyapatite)
Arrangements of Bone Tissue
– Compact (cortical)
Arrangements of Bone Tissue – Compact (cortical) – Spongy (cancellous)
Compact Bone Tissue
– Location
Compact Bone Tissue – Location On bone surfaces
Compact Bone Tissue – Location On bone surfaces (matrix arranged as
Compact Bone Tissue – Location On bone surfaces (matrix arranged as circumferential lamellae)
Compact Bone Tissue – Location On bone surfaces (matrix arranged as circumferential lamellae) In shafts of long bones
Compact Bone Tissue – Location On bone surfaces (matrix arranged as circumferential lamellae) In shafts of long bones (matrix arranged as
Compact Bone Tissue – Location On bone surfaces (matrix arranged as circumferential lamellae) In shafts of long bones (matrix arranged as concentric
Compact Bone Tissue – Location On bone surfaces (matrix arranged as circumferential lamellae) In shafts of long bones (matrix arranged as concentric and interstitial lamellae)
– The osteon
– The osteon (Haversian system):
– The osteon (Haversian system): unit structure of thick compact bone Haversian canal Lacuna Canaliculi *
Arrangements of Bone Tissue – Compact Bone Tissue
Arrangements of Bone Tissue – Compact Bone Tissue – Spongy (cancellous) bone tissue
Arrangements of Bone Tissue – Compact Bone Tissue – Spongy (cancellous) bone tissue Location: within bones
Arrangements of Bone Tissue – Compact Bone Tissue – Spongy (cancellous) bone tissue Location: within bones Consists of branching plates called trabeculae
Arrangements of Bone Tissue – Compact Bone Tissue – Spongy (cancellous) bone tissue Location: within bones Consists of branching plates called trabeculae
Arrangements of Bone Tissue – Compact Bone Tissue – Spongy (cancellous) bone tissue Location: within bones Consists of branching plates called trabeculae Bone marrow found between the trabecular spaces
Periosteum
– Fibrous layer
Periosteum – Fibrous layer – Cellular layer
Periosteum – Fibrous layer – Cellular layer Source of new oesteoblasts
Bone Tissue Remodelling
– Osteoblasts
Bone Tissue Remodelling – Osteoblasts – Osteoclasts *
Review Classification of CT – CT “Proper” – Supporting CT
Review Classification of CT – CT “Proper” – Supporting CT – Fluid CT
Review Classification of CT – CT “Proper” – Supporting CT – Fluid CT Blood
Review Classification of CT – CT “Proper” – Supporting CT – Fluid CT Blood Lymph
Blood
Blood =
Blood = Formed elements
Blood = Formed elements + plasma
– Formed elements
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”)
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S (erythrocytes)
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S (erythrocytes) WBC’s
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S (erythrocytes) WBC’s (leukocytes)
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S (erythrocytes) WBC’s (leukocytes) platelets
Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S (erythrocytes) WBC’s (leukocytes) platelets (thrombocytes)
Red Blood Cells
– “bags” of hemoglobin *
White Blood Cells
– Granulocytes
White Blood Cells – Granulocytes Neutrophils
White Blood Cells – Granulocytes Neutrophils Eosinophils
White Blood Cells – Granulocytes Neutrophils Eosinophils Basophils
White Blood Cells – Granulocytes Neutrophils Eosinophils Basophils – Agranulocytes
White Blood Cells – Granulocytes Neutrophils Eosinophils Basophils – Agranulocytes Lymphocytes
White Blood Cells – Granulocytes Neutrophils Eosinophils Basophils – Agranulocytes Lymphocytes Monocytes
White Blood Cells – Granulocytes Neutrophils Eosinophils Basophils – Agranulocytes Lymphocytes Monocytes Basophil Neutrophil Eosinophil Lymphocyte Monocyte
Platelets (Thrombocytes)
REVIEW Blood = Formed elements + plasma – Formed elements (AKA “blood solids”) RBC’S (erythrocytes) WBC’s (leukocytes) platelets (thrombocytes)
Platelets (Thrombocytes) – Derived from megakaryocytes
Hemopoiesis – All formed elements develop from
Hemopoiesis – All formed elements develop from hemopoietic stem cells
Hemopoiesis – All formed elements develop from hemopoietic stem cells – Erythropoiesis
Hemopoiesis – All formed elements develop from hemopoietic stem cells – Erythropoiesis: regulated by erythropoiten (EPO)
Hemopoiesis – All formed elements develop from hemopoietic stem cells – Erythropoiesis: regulated by erythropoiten (EPO) – Leukopoiesis
Hemopoiesis – All formed elements develop from hemopoietic stem cells – Erythropoiesis: regulated by erythropoiten (EPO) – Leukopoiesis: regulated by numerous factors
Plasma
– Water
Plasma – Water – Electrolytes
Plasma – Water – Electrolytes – Organic nutrients
Plasma – Water – Electrolytes – Organic nutrients – Organic wastes
Plasma – Water – Electrolytes – Organic nutrients – Organic wastes – Plasma proteins
Albumin Globulins Clotting factors (e.g. fibrinogen) Regulatory hormones