Dr. Yingtian Pan’s Lab Unjoo Lee. About him  He is an associate Professor

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Presentation transcript:

Dr. Yingtian Pan’s Lab Unjoo Lee

About him  He is an associate Professor

About his research  Dr. Pan is interested in early-stage epithelial cancer detection, diagnosis of cartilage injury and repair, and assessment of engineering tissue growth. In addition, his lab studies skin dehydration, geriatric incontinence, fluorescence imaging and light microscopy.

About his research  Optical coherence tomography (OCT) a new noninvasive optical diagnostic technique that provides depth-resolved images of tissues with resolution of about 2-10 µm at depths of up to several mm. This technique was introduced in 1991 to perform tomographic imaging of the human eye by Fujimoto's group at MIT. The basic principle of the OCT is to detect backscattered photons from a tissue of interest within a coherence length of the source by using a two-beam interferometer.

About his research  Optical coherence tomography (OCT) OCT imaging is somewhat analogous to ultrasound B-mode imaging except that it uses light, not sound.  Briefly, light from a broadband source (a laser with low coherence) is aimed at objects to be imaged using a beam splitter.  Light scattered from the tissue is combined with light returned from the reference arm, and a photodiode detects the resulting interferometric signal.

About his research  Optical coherence tomography (OCT) OCT imaging is somewhat analogous to ultrasound B-mode imaging except that it uses light, not sound.  Interferometric signals can be formed only when the optical path length in the sample arm matches the reference arm length within coherence length of the source.  By gathering interference data at points across the surface, cross-sectional 2D and 3D images can be formed in real time with resolution of about 2-10 µm at depths up to several millimeters, depending on the tissue optical properties.

About his research  Optical coherence tomography (OCT) Time domain OCT

About his research  Optical coherence tomography (OCT) Fourier domain OCT using a broadband laser source (typical FWHM > 75 nm) with a grating and a photodiode array in the detection arm

About his research  Optical coherence tomography (OCT) Swept source OCT using a rapidly tunable, narrow-linewidth laser source over a broad optical bandwidth with a single photodiode in the detection arm.

About his research  Laser scanning endoscope

About his research  Laser scanning endoscope

About his research  Laser scanning endoscope Color SFE images taken at 10 Hz frame rate, (top-left) teeth of the author, (top-right) scar on skin of the author, (bottom-left) live flower, and (bottom-right) dried sheep lung. All 500-line images are generated from a 250 spiral pattern.