Blood
Components of Blood Whole blood RBCs WBCs Platelets: cell fragments that aid in clotting Plasma 90% water (allows materials to dissolve) Amino acids, glucose, hormones, vitamins, salts, waste Concentrations allows diffusion in/out of blood stream
Click picture to play
Platelets Form clots when bleeding Proteins form a web to trap cells & platelets
White Blood Cells Remove foreign invaders & dead cells Able to move through body tissue
Red Blood Cells Produced from stem cells in bone marrow Lose nucleus as they mature Transport O2 to cells; remove CO2 O2 binds to hemoglobin proteins Dead cells filtered by liver & spleen
Sickle Cell Normal
ABO Blood Groups Proteins on blood cells (antigens) determine blood type Antigens: proteins on cells that identify cells as foreign or natural on the surface of RBCs Antibodies: proteins from WBCs to attack invaders in the blood plasma
Group A blood A antigens on the surface of your RBCs B antibodies in your blood plasma
Group B blood B antigens on the surface of your RBCs A antibodies in your blood plasma
Group AB blood A and B antigens on the surface of your RBCs no A or B antibodies at all in your blood plasma
Group O blood No A or B antigens on the surface of your RBCs both A and B antibodies in your blood plasma
If you have type A blood, can you receive: Type B blood from a donor? Type AB blood from a donor? Type O blood from a donor?
If you have type B blood, can you receive: Type A blood from a donor? Type AB blood from a donor? Type O blood from a donor?
If you have type AB blood, can you receive: Type A blood from a donor? Type B blood from a donor? Type O blood from a donor?
If you have type O blood, can you receive: Type A blood from a donor? Type B blood from a donor? Type AB blood from a donor?
Rh Factors Rh+ Rh- Protein found in blood Can receive Rh+ or Rh- blood Lack protein in blood Only receive Rh- blood
Francis was just in a bad accident and lost a lot of blood Francis was just in a bad accident and lost a lot of blood. He is blood type B+. Can you help save him?
Blood type B+ Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh
Vein Can we give Francis B+ blood? Will Francis’ A antibodies attack? No. Can he accept B+ blood? Yes. You can always accept your own blood type. Vein A antibody A antibody A antibody A antibody
Vein Can we give Francis B- blood? Will Francis’ A antibodies attack? No. Can he accept B- blood? Yes. Since the A antibodies only attack A antigens, there is no danger. Vein A antibody A antibody A antibody A antibody
Vein No. Francis’ A antibodies will attack the A antigens. Can we give Francis A+ blood? Will Francis’ A antibodies attack? Yes. Can he accept A+ blood? No. Francis’ A antibodies will attack the A antigens. Vein A antibody A antibody A antibody A antibody
Vein No. Francis’ A antibodies will attack the A antigens. Can we give Francis A- blood? Will Francis’ A antibodies attack? Yes. Can he accept A- blood? No. Francis’ A antibodies will attack the A antigens. Vein A antibody A antibody A antibody A antibody
Vein No. Francis’ A antibodies will attack the A antigens. Can we give Francis AB+ blood? Will Francis’ A antibodies attack? Yes. Can he accept AB+ blood? No. Francis’ A antibodies will attack the A antigens. Vein A antibody A antibody A antibody A antibody
Vein No. Francis’ A antibodies will attack the A antigens. Can we give Francis AB- blood? Will Francis’ A antibodies attack? Yes. Can he accept AB- blood? No. Francis’ A antibodies will attack the A antigens. Vein A antibody A antibody A antibody A antibody
Can we give Francis O+ blood? Will Francis’ A antibodies attack? No. Can he accept O+ blood? Yes. Since the A antibodies only attack A antigens, there is no danger. Vein A antibody A antibody A antibody A antibody
Can we give Francis O- blood? Will Francis’ A antibodies attack? No. Can he accept O- blood? Yes. Since the A antibodies only attack A antigens, there is no danger. Vein A antibody A antibody A antibody A antibody
Blood Type Internet Lesson
Sebastian was just involved in an accident at work and lost a lot of blood. He is blood type A-. Can you help save him?
Blood type A- Antigens: Which does he have? A B Rh Antibodies: Which does he have? A B Rh
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept A- blood? Yes. You can always accept your own blood type. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept A+ blood? No. Sebastian’s Rh antibodies will attack the Rh antigens. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept B- blood? No. Sebastian’s B antibodies will attack the B antigens. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept B+ blood? No. Sebastian’s B and Rh antibodies will attack the B and Rh antigens. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept AB- blood? No. Sebastian’s B antibodies will attack the B antigens. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept AB+ blood? No. Sebastian’s B and Rh antibodies will attack the B and Rh antigens. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept O- blood? Yes. Sebastian’s antibodies do not attack these antigens. Vein B antibody B antibody Rh antibody Rh antibody
This person has A- blood type because of the A antigens This person has A- blood type because of the A antigens. Can he accept O+ blood? No. Sebastian’s Rh antibodies will attack the Rh antigens. Vein B antibody B antibody Rh antibody Rh antibody
Blood type AB+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type O+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type AB- Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type B+ Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh
Blood type O- Antigens: Which does they have? A B Rh Antibodies: Which does they have? A B Rh