Rieger's syndrome Description: A genetically determined syndrome of malformations of the anterior chamber of the eye and the teeth, combining features.

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Rieger's syndrome Description: A genetically determined syndrome of malformations of the anterior chamber of the eye and the teeth, combining features of the Axenfeld syndrome with oligodontia. Eye anomalies consist of posterior embryotoxon (an opaque ring at the margin of the cornea), a prominent Schwalbe ring, iris adhesion to the Schwalbe line, hypoplasia of the anterior stroma of the iris, and occasional glaucoma. Tooth anomalies include anondontia vera and microdontia.

The Pituitary Gland

kirbylab.duhs.duke.edu/resources.htm Mouse Development

GeneGene productAssay lacZβ-galactosidaseHistochemical test uidAβ-glucuronidaseHistochemical test luxLuciferaseBioluminescence GFPGreen fluorescent protein Fluorescence Reporter Gene Assay

PITX2-LACZ Staining of mouse embryo day 11 PITX2: bicoid-related transcription factor

Transgenic Mouse (Tg Mouse)

Chromatin Immunoprecipitation (ChIP) assays are used to evaluate the association of proteins with specific DNA regions.

The WNT Signaling Pathway