The iPlant Collaborative Community Cyberinfrastructure for Life Science Tools and Services Workshop …and Environments.

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Presentation transcript:

The iPlant Collaborative Community Cyberinfrastructure for Life Science Tools and Services Workshop …and Environments

genotype-phenotype relationship--consistent and additive? Environments—what and why most alleles are context-dependent! How do we find alleles that are only detectable in certain cases?

Mixed models are a flexible, powerful way to search for correlation between snp and trait Intercept Subpop membership and effect (fixed) Marker score and effect (fixed) Polygenic effect (random) u ~ MVN(0, K*sigma2_u) Random residual

Mixed models are a flexible, powerful way to search for correlation between snp and trait Intercept Subpop membership and effect (fixed) Marker score and effect (fixed) Polygenic effect (random) u ~ MVN(0, K*sigma2_u) Random residual Environment-specific SNP allele effect And add a term for the population-specific SNP allele x environment…. environment

The iPlant Collaborative is funded by a grant from the National Science Foundation Plant Cyberinfrastructure Program (#DBI ).

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