Cellular Reproduction

Cell Reproduction What is cell reproduction? How many cells make up your body? How does the chromosome transmit information from one generation to another?

DNA is a molecule that contains the genetic code of an organism.

A GENE is a segment of DNA that transmits information from parent to offspring. A single molecule of DNA has thousands of genes lines up end to end. Like the strands of a sock…DNA coils tightly before cell division. If it were straight the DNA would be approximately 5 cm long. (2 inches)

Gene When the cell is going to divide the DNA coils up into a dense chromosome structure.

Chromosome Cellular structure on which genes are located. Pg. 212

Chromosomes are 40% DNA and 60% protein that supports the DNA (histones). Scientists have mapped the 100,000 genes that make up the chromosomes of humans.

A set of chromosomes from a female

Chromosome structure

Chromatids are the two copies of each chromosome. Centromeres are protein disks that attach the two chromatids.

A karyotype is the collection of chromosomes found in an organisms cells. Arranged in order of size and shape.

Karyotype Cont. It is a display of chromosomes of a single cell. To obtain it, the cell is stained, then a picture is taken of it through a microscope just before cell division, when the chromosomes are easiest to see.

All the cells in our body other than gametesSomatic cells contain 23 different chromosomes, but contain two copies of each, a total of 46 chromosomes. All the cells in our body other than gametes Homologous chromosomes are the two copies of each chromosome type (for example chromosomes 13 are homologous because they are the same type.

Homologous Chromosomes & Somatic Cells

Homologous Chromosomes Chromosomes that are similar in shape, size, and the genes they carry. They do NOT have the same types of DNA sequence!

Allele An alternate form of a gene that is located at a specific position on a specific chromosome.

A homologue is a half set of chromosomes. One chromosome of a pair. Diploid cells contain two homologues. The symbol for diploid is 2n. All somatic cells are diploid. It contains exactly two copies of each chromosome.

Haploid cells contain only one homologue; if it contains exactly half of a species’ typical full set of genetic material. Only sex cells are haploid (n).

An organism’s reproductive cells, such as sperm or egg cellsGametes are sex cells and are haploid. An organism’s reproductive cells, such as sperm or egg cells

Draw the following table symbolCells# of homologues Diploid2nSomatic2 (46 chromosomes) 23 pairs haploidngametes1 (23 chromosomes) 23 individual chromosomes

A fertilized egg cell, the first cell of a new individual. A zygote is the fusion of a haploid sperm cell and a haploid egg cell. A fertilized egg cell, the first cell of a new individual.

Chromosome numbers of various organisms OrganismNumber of Chromosomes Penicillium1-4 Saccharomyces (yeast)18 Mosquito6 Housefly12 Garden Pea14 Corn20 Adder’s tongue fern 1,262 Frog26 Human46 Orangutan48 Dog78

Adders Tongue Fern

Each Chromosome is important to the development of a normal organism. Monosomy is a condition in which a diploid cell is missing a chromosome. Most embryos will not survive if missing a chromosome.

Down Syndrome: Jared has a condition in which his 21 st chromosome number is three instead of two.(trisomy 21 or down syndrome). Pg 335

In Amniocentesis Amniotic fluid is tested for chromosome problems. The normal frequency of down syndrome is 1 in For couples who are older than 30 it is 1 in In couples it is 1 in 750. In couples older than 45 the risk is 1 in 16.

Alterations in chromosomes usually lead to mutations. There are four types of alterations. Mutations: alterations in chromosomes. PG. 306 Deletion is a process in which a chromosome is damaged as fragments break off the chromosome and are lost. Duplication occurs as fragments attach to the homologous chromosomes.

Inversion happens when fragments of the original chromosome attach in reverse order. Translocation occurs when a fragment may join a non-homologous chromosome.

not directly involved in determining the sex. Of the 23 pairs of chromosomes in human somatic cells, 22 pairs are the same. These chromosomes are called autosomes-not directly involved in determining the sex. The Sex Chromosomes, X,Y, determine the sex of the organism. These chromosomes are called sex chromosomes. A combination of XX is a female. A combination of XY is a male Because an egg cell carries only the X chromosome and the sperm cell carries either X or Y the sex of an offspring is determined by the male sex cells.

Meiosis A form of cell division that halves the number of chromosomes when forming specialized reproductive cells, such as gametes or spores. Results in four haploid cells pg. 273

Review Link Meiosis

Lab Partner Questions: Can meiosis be asexual? What phase is responsible for the law of independent assortment? When will crossing over occur?

Crossing Over The exchange of reciprocal segments of DNA by chromosomes at the beginning of meiosis pg. 277

The separation of genes during crossing over occurs more frequently between genes that are far apart on a chromosome than for genes that are close together. When these chromosomes segregate in meiosis, they form gametes that have completely new combinations of alleles.

Meiosis review

Reviewing Information

Binary fission is a type of asexual reproduction that produces identical offspring. (happens in prokaryotic cells such as bacteria)

When Eukaryotic cells split the internal organelle must also divide and the process is much more complex. This process is known as the cell cycle.

Cell Cycle is a diagram of the growth and division of a cell.