Nervous System Pharmacology Review 26 December :45 AM

Adrenocorticotropin (ACTH) Anterior pituitary hormone Anticonvulsant Stimulates synthesis and release of cortisol

Alfentanil Opioid General anaesthetic Intravenous anaesthetic

Amantadine Antiviral Antiparkinson Treatment of Influenza A Inhibits replication at the stage of uncoating Inhibits dopamine release

Amitriptyline Tricyclic antidepressant (TCA)

Amphetamine Indirect sympathomimetic Drug of abuse ADD treatment Stimulant

Atropine Anticholinergic Antimuscarinic Treatment for bradycardia, diarrhea, cholinesterase poisoning

Baclofen Skeletal muscle relaxant Anxiolytic GABA B agonist

Benztropine Anticholinergic Antiparkinson Muscarinic receptor antagonist

Bethanecol Cholinomimetic Muscarinic agonist Induces defecation and urination Bronchoconstrictor

Bromocriptine Antiparkinson Dopamine (D 2 ) agonist Inhibits prolactin release

Brupropion Second generation antidepressant

Buprenorphine Opioid Partial agonist

Buspirone Sedative/hypnotic Anxiolytic

Butorphanol Opioid Analgesic  receptor partial agonist or antagonist

Carbamazepine Anticonvulsant

Carbidopa Antiparkinson Peripheral dopa decarboxylase inhibitor

Celecoxib NSAID Anti-inflammatory Cyclooxygenase 2 (COX-2) inhibitor

Chloral hydrate Sedative/Hypnotic General anaesthetic Acts on GABA A receptor complex Similar to barbiturates

Chlordiazepoxide Sedative/hypnotic Anxiolytic Benodiazepine Acts on GABA A receptor complex

Chlorpromazine Antipsychotic Phenothiazine

Clozapine Antipsychotic

Cocaine Indirect sympathomimetic Drug of abuse Topical anaesthetic Stimulant Local anaesthetic

Codeine Opioid Analgesic Weak agonist

Dantrolene Skeletal muscle relaxant Ryanodine receptor antagonist Treatment for malignant hyperthermia

Deprenyl/selegiline Antiparkinson Monoamine oxidase B inhibitor (MAO-I) Potentiates effects of L-Dopa

Desipramine Tricyclic antidepressant (TCA)

Dextromethorphan Opioid Antitussive

Diazepam Sedative/hypnotic Anxiolytic Anticonvulsant Benzodiazepine Acts on GABA A receptor complex

Diphenoxylate docusate Antidiarrheal Opiate

Enflurane General anaesthetic Inhaled anaesthetic

Entacapone Antiparkinson Peripheral catechol-o- methyltransferase inhibitor

Ephedra (Ma Huang) Dietary supplement Amphetamine-like stimulant

Ethanol Drug of abuse Sedative

Ethosuximide Anticonvulsant

Etomidate General anaesthetic Intravenous anaesthetic

Fentanyl Opioid Analgesic  receptor agonist

Flumazenil Benzodiazepine antagonist Acts on GABA A receptor complex

Fluoxetine Antidepressant Selective serotonin reuptake inhibitor (SSRI)

Flurazepam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

Ginko biloba Dietary supplement Treatment of Alzheimer symptoms

Glutethimide Sedative/Hypnotic

Haloperidol Antipsychotic

Halothane General anaesthetic Inhaled anaesthetic

Heroin Drug of abuse Opioid

Imipramine Indirect sympathomimetic Tricyclic antidepressant (TCA) Antimicturant

Isoflurane General anaesthetic Inhaled anaesthetic

Kava kava Dietary supplement Stress relief and treatment of insomnia

Ketamine General anaesthetic Drug of abuse Sedative

Levodopa Antiparkinson Dopamine precursor

Lidocaine Class I antiarrhythmic Local anaesthetic Na + channel blocker (activated and inactivated channels)

Lithium Antidepressant Used to treat manic/depressive disorder

Loperamide Antidiarrheal Opiate

Lorazepam Anxiolytic Anticonvulsant Benzodiazepine Acts on GABA A receptor complex

Lysergic acid diethylamide (LSD) Drug of abuse Hallucinogen

Marijuana Drug of abuse Cannabinoid

Meperidine Opioid analgesic  receptor agonist

Mepivacaine Local anaesthetic

Meprobamate Sedative/hypnotic Anxiolytic

Metamphetamine Drug of abuse Stimulant

Methadone Opioid  receptor agonist

Morphine Opioid Analgesic  receptor agonist

Nalbuphine Opioid antagonist  receptor antagonist

Nalmefene Opioid antagonist

Nalorphine Opioid antagonist

Naloxone Opioid antagonist

Naltrexone Opioid antagonist

Neostigmine Anticholinesterase Vasodilator Treatment for myaesthenia gravis Promotes defecation and urination Bronchoconstrictor

Nicotine Cholinomimetic Drug of abuse Nicotinic receptor agonist (skeletal muscle contraction) Stimulant Smoking cessation medication

Nitrous oxide General anaesthetic Inhaled anaesthetic

Nortriptyline Tricyclic antidepressant (TCA)

Oxazepam Sedative/hypnotic Anxiolytic Benzodiazepine Acts on GABA A receptor complex

Oxybutinin Anticholinergic Muscarinic receptor antagonist Prevents urination

Oxycodone Analgesic Opioid agonist

Paraldehyde Sedative/Hypnotic

Pentazocine Opioid analgesic  receptor partial agonist or antagonist

Pentobarbital Sedative/Hypnotic Barbiturate

Phencyclidine (PCP) Drug of abuse Hallucinogen

Phenobarbital Sedative/Hypnotic Anticonvulsant Barbiturate

Phenytoin Anticonvulsant Class I antiarrhythmic Na + channel blocker (inactivated channels)

Pramipexole Antiparkinson Dopamine agonist (non-ergot)

Primidone Anticonvulsant

Procaine Local anaesthetic

Propofol General anaesthetic Intravenous anaesthetic

Resperidone Antipsychotic

Ropinirole Antiparkinson Dopamine agonist (non-ergot)

Sertraline Antidepressant Selective serotonin reuptake inhibitor (SSRI)

Sildenafil Vasodilator Promotes erection

St. John’s Wort Dietary supplement Antidepressant

Sufentanil Opioid General anaesthetic Intravenous anaesthetic

Temazepam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

Tetracaine Local anaesthetic

Thiopental General anaesthetic Ultra-short-acting barbiturate

Thioridazine Antipsychotic Phenothiazine

Thiothixene Antipsychotic

Tolterodine Anticholinergic Muscarinic receptor antagonist Prevents urination

Tranylcypromine Antidepressant Monoamine oxidase inhibitor (MAO-I)

Triazolam Sedative/Hypnotic Benzodiazepine Acts on GABA A receptor complex

Trifluoperazine Antipsychotic Phenothiazine

Trihexyphenidyl Antiparkinson Antimuscarinic

Valproic acid Anticonvulsant

Vigabatrin Anticonvulsant Irreversible GABA aminotransferase inhibitor

Zolpidem Sedative/Hypnotic Non-benzodiazepine