Prof. Dalia M. Mohsen Prof. In Microbiology. Is a disease of the human immune system. Types: It have two type (HIV-1 and HIV-2 ) HIV-1 and HIV-2 differ.

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Prof. Dalia M. Mohsen Prof. In Microbiology

Is a disease of the human immune system. Types: It have two type (HIV-1 and HIV-2 ) HIV-1 and HIV-2 differ in genome organization. The proteins of HIV-2 are only identical to those of HIV-1

Prof. Dalia M. Mohsen Prof. In Microbiology

HIV is transmitted by three main routes: Sexually blood and blood products. Mother-to-child

Prof. Dalia M. Mohsen Prof. In Microbiology Target site: Lymphocytes Macrophages Dendritic cell Symptoms This lead to drop of total number of CD4T- cells The immune function become deficient.

Prof. Dalia M. Mohsen Prof. In Microbiology Some viruses cause hepatitis as part of a general infection but the main targets of the true hepatitis viruses are the hepatocyte themselves. These hepatitis viruses include: Hepatitis A Virus (HAV) Hepatitis B Virus (HBV) Hepatitis C Virus (HCV)

Prof. Dalia M. Mohsen Prof. In Microbiology General characteristic: It is a non enveloped. Single strand-RNA virus. Icosahedral virus. It is pathogenic to man and. Incubation period is 2-6 weeks.

Prof. Dalia M. Mohsen Prof. In Microbiology

It is an acute disease characterized by non- supportive enlargement of the parotid glands The virus has a single serotype

Prof. Dalia M. Mohsen Prof. In Microbiology Infection occurs by respiratory droplets. Primary multiplication occurs in the respiratory mucosa followed by viraemia and localization of virus in the parotids and other salivary glands. It may affect the testes, ovaries, pancreas and the CNS. Some cases are subclinical. The incubation period is 18 days Followed by fever, malaise, anorexia, and swelling of parotid gland. Meningitis may complicate some cases. Immunity is permanent after a single infection.

Prof. Dalia M. Mohsen Prof. In Microbiology