Noninvasive Quantification of Human Nucleus Pulposus Pressure with Use of T1ρ-Weighted Magnetic Resonance Imaging by An M. Nguyen, Wade Johannessen, Jonathon.

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Noninvasive Quantification of Human Nucleus Pulposus Pressure with Use of T1ρ-Weighted Magnetic Resonance Imaging by An M. Nguyen, Wade Johannessen, Jonathon H. Yoder, Andrew J. Wheaton, Edward J. Vresilovic, Arijitt Borthakur, and Dawn M. Elliott J Bone Joint Surg Am Volume 90(4): April 1, 2008 ©2008 by The Journal of Bone and Joint Surgery, Inc.

Representative T2-weighted (left) and T1ρ-weighted (right) images of the spine of a fifteen-year- old male donor. An M. Nguyen et al. J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.

Correlation between T1ρ relaxation time and degenerative grade (A) and between T1ρ relaxation time and age (B). An M. Nguyen et al. J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.

Comparison of T1ρ relaxation time (A), swelling pressure (Psw) (B), and sulfated- glycosaminoglycan content (s-GAG) per dry weight between non-degenerated and degenerated discs (C). An M. Nguyen et al. J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.

Correlation between T1ρ relaxation time and swelling pressure (Psw) (A) and between swelling pressure and sulfated-glycosaminoglycan content (s-GAG) per dry weight (B). An M. Nguyen et al. J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.

Correlation between T1ρ relaxation time and sulfated-glycosaminoglycan content (s-GAG) per dry weight (A) and between T1ρ relaxation time and water content (B). An M. Nguyen et al. J Bone Joint Surg Am 2008;90: ©2008 by The Journal of Bone and Joint Surgery, Inc.