SMA (spinal muscular atrophy) is a rare recessive genetic disorder. Using a punnet square calculate the chance of a heterozygous (Both are carriers) couple having a child with the disease. N= normal central nervous system n=spinal muscular atrophy Blue eyes are due to a recessive allele (b). What is the chance of 2 heterozygous brown eyed people having a blue eyed child. B=Brown eye color b=blue eye color HAPPY WEDNESDAY Small Group CHAMPS G2 Computer BELLWORK: Read the following article (at your desk on yellow paper) about SMA and complete both Punnett squares to the right.

BBBb bb NNNn nn Now what is the chance of the couple having a blue eyed child with the disorder? N= normal central nervous systemB=Brown eye color n=spinal muscular atrophyb=blue eye color ¼ x ¼ = 1/16 1 out of 16 chance of having blue eyes with the disorder.

BBBb bb NNNn nn Now what is the chance of the couple having a brown-eyed child without the disorder? N= normal central nervous systemB=Brown eye color n=spinal muscular atrophyb=blue eye color ¾ x ¾ = 9/16 9 out of 16 chance of having blue eyes with the disorder.

Unit 5 – Genetics Definitions Due Thursday (12/3/15) All Parts Due Thursday (12/10/15) 1.Allele 2.Co-Dominance 3.Dihybrid Cross 4.Dominant 5.Gene 6.Genotype 7.Gregor Mendel 8.Heterozygous 9.Homozygous 10.Hybrid 11.Incomplete Dominance 12.Monohybrid 13.Multiple Alleles 14.Pedigree 15.Phenotype 16.Polygenic 17.Punnett Square 18.Purebred 19.Recessive 20.Sex-linked Traits PG 70

Collect Today Page 82 – Bikini Bottom Genetics Page 80 – Pedigree Practice CORRECTIONS Assigned Page 70 – Notecard ALL PARTS (TOMORROW) Most Missed MAKE-UP Quiz (TOMORROW) Page 85 – Incomplete Practice (TOMORROW) Genetics MAKE-UP Quiz (Monday) Page 77 – Family Tree Project Part 2 (Monday) Genetics Exam (Monday) Genetics Vocabulary MAKEUP Quiz (WEDNESDAY) Late Page 80 – Pedigree Practice (-50%) Page 74 – Family Tree Project Part 1 (-50%)

Essential Question What other forms of dominance exist in organisms? Standard B6F - Predict possible outcomes of genetic combinations such as Non-Mendelian Genetics. PG 83/85 Direct Instruction CHAMPS

Mendel’s principles form the basis of the modern science of genetics. The inheritance of biological characteristics is determined by individual units called genes. Genes are passed from parents to their offspring.

In cases in which two or more forms (alleles) of the gene for a single trait exist, some forms of the gene may be dominant and others may be recessive. In most sexually reproducing organisms, each adult has two copies of each gene. These genes are segregated from each other when gametes are formed. The alleles for different genes usually segregate independently of one another.

There are exceptions to most of Mendel’s principles. All genes do not show simple patterns of dominant or recessive alleles.

Cases in which one allele is not completely dominant over another are called incomplete dominance. In this case, the heterozygous phenotype looks like a blending of the two homozygous phenotypes.

Incomplete Dominance Example Spongebob loves growing flowers for his gal pal, Sandy. She loves the Poofkin flowers—red, purple, and blue! Interestingly enough, the Poofkin flowers display incomplete dominance in their genes for color. 1. Using “R” for red and “B” for blue, what would be the genotypes for the following phenotypes? red: ______ purple: _____blue: _____ 2. Complete a Punnett square for a red Poofkin and a purple Poofkin. PG 85 RRBBRB Male:Female:RR RB

HW: Incomplete Practice PG 85 Essential Question How does the genotype change with a dihybrid cross?

Spongebob loves growing flowers for his gal pal, Sandy. She loves the Poofkin flowers—red, purple, and blue! Interestingly enough, the Poofkin flowers display incomplete dominance in their genes for color. 1. Using “R” for red and “B” for blue, what would be the genotypes for the following phenotypes? red: ______ purple: _____white: _____ 2. What are the genotypic and phenotypic ratios when you cross a purple radish with a white radish? PG 84 RR WW RW Male:Female:RW WW Non-Mendelian Genetics Practice Problems Incomplete Dominance/Codominance Blood Typing Problems Sex-Linked Problems