1 H-NMR SPECTROSCOPY 2008

Unknown C 4 H 8 O 2

1 H-NMR

1 H-NMR - Theory 3.1 Nuclear Spin States 3.2 Nuclear Magnetic Moments 3.3 Absorption of Energy

1 H-NMR - Theory

3.4 Absorption / Resonance

1 H-NMR 3.7 The Spectrometer The FID (Free Induction Decay) Fourier Transform (time domain signal converted to frequency domain signal)

1 H-NMR – Chemical Shift Chemical equivalence Hybridization effects Electronegativity Effects Shielding (vs deshielded) hexane

1 H-NMR Chemical Shift Hybridization effects Electronegativity Effects

1 H-NMR – Chemical Shift

Acidic and Exchangeable Protons - Chemical Shift Ranges Exchangable proton Chemical Shift Range (ppm) AcidsRCOOH PhenolsArOH (as high as 9.0) AlcoholsROH0.5 – 5.0 AminesRNH20.5 – 5.0 AmidesRCONH

1 H-NMR – Chemical Shift Magnetic Anisotropy (3.12)

1 H-NMR – Coupling Spin-Spin Splitting (3.13)

1 H-NMR – Coupling Spin-Spin Splitting (3.13)

1 H-NMR – Coupling Spin-Spin Splitting (3.13)

1 H-NMR – Coupling The Coupling Constant (3.17)

1 H-NMR – Coupling The Coupling Constant (3.17)

1 H-NMR – Coupling The Coupling Constant (3.17)

1 H-NMR – Coupling The Coupling Constant (3.17)

1 H-NMR – Coupling The Coupling Constant (3.17)

C 6 H 5 -CH=CH-CO 2 CH 3 C 10 H 10 O 2 1 H-NMR – Coupling - The Coupling Constant (3.17)

1 H-NMR - Aromatics (3.19C)

1 H-NMR 4-n-propylphenol

1 H-NMR - Aromatics Chemical Shift Calculation 6.75 vs 7.03 ppm

1 H-NMR – Unknown (C 6 H 4 Br)

1 H-NMR – Unknown (C 6 H 6 BrN)

C7H7OBr 1 H-NMR – Unknown (C 7 H 7 BrO)

Unknown A (C 7 H 14 ) Unknown B (C 7 H 14 ) 1 H-NMR – Unknown isomers