Embryology Doc. MUDr. Ing. RNDr. Peter Celec, DrSc., MPH

Slides:



Advertisements
Similar presentations
Summer 2007 Workshop in Biology and Multimedia for High School Teachers.
Advertisements

Different Sources of Stem Cells National Academy of Sciences Embryonic Stem Cells Embryonic Stem Cells (Therapeutic Cloning) Adult Stem Cells AttributesIn.
DNA TECHNOLOGY: Part 1 Cloning & Stem Cell Research Nova video.
Cell Differentiation. Learning Objectives  Describe the process of differentiation.  Define stem cells and explain their importance.  Identify the.
1 Lecture 2: Nuclear Reprogramming. Nuclear Reprogramming 2 Switch of gene expression from one cell type to another Switch from a differentiated, specialized.
Human Development starts with just 1 cell – the fertilized egg. This cell divides to produce 2 ‘daughter cells’. These daughters divide, and their daughters.
Cloning and Stem Cells. A wood panel painting depicting the limb transplantation miracle by Saints Cosmas and Damian. According to legend Cosmos and Damian.
STEM CELLS: The Upside and Downside of Stem Cell Science Human ES cell colony: picture provided by Dr. Toshihiko Ezashi.
STEM CELLS Image Credit: Mesenchymal precursor cellsMesenchymal precursor cells.
Vittorio Bruno BIOE 506 4/19/2010 Stem Cells. Contents 2 Introduction Concepts Potential Conclusions References.
Stem Cells. Cell Differentiation and Stem Cells Major Topics for Discussion: 1) What are Stem Cells? 2) What are the major types of Stem Cells and where.
Stem Cell Notes IB Biology HL 1 Mrs. Peters Winter 2014.
CELL TECHNOLOGY Stem Cells Definition
Epigenetics: Nuclear transplantation & Reprogramming of the genome
Student Society for Stem Cell Research February 27, 2008 Virginia Commonwealth University.
Stem Cells: Myths, Facts, and Ethics
Have web quest out. Quiz on Tuesday.
1 Cord Blood Stem Cells Cord Blood Stem Cells Marwan Alhalabi MD. PhD Professor in Faculty of Medicine Damascus - University And Medical Director Orient.
Determinant Development
RNA INTERFERENCE. Accidental Discovery Pigment enhancing gene.
New Reproductive Technology Juan Felipe Pardo y Paulina Campo 10F.
THE BIOLOGY OF STEM CELLS. The Biology of All Cells DNAmRNAProtein transcriptiontranslation 3’polyA tail.
Chapter 3: Cells Part IV: The Cell Cycle Control of Cell Division Stem and Progenitor Cells.
THE BIOLOGY OF STEM CELLS Melissa Henriksen, PhD Clare Boothe Luce Assistant Professor Biological Sciences.
Cloning and Stem Cells. A wood panel painting (~1500A.D.) depicting the limb transplantation miracle by Saints Cosmos and Damian. According to legend.
Trends in Biotechnology Revision Questions. In 2005, ES-like cells were generated using four factors. The resulting cells were called iPS cells. What.
DOLLY THE SHEEP AND HER FIRST LAMB CALLED BONNY Somatic Cell Nuclear Transfer (SCNT) By Caroline Kim.
Objectives Define a clone. Outline a technique for cloning using differentiated animal cells. Discuss the ethical issues of therapeutic cloning in humans.
 Stem Cells and Cloning. Stem Cells  Stem Cell: a cell that can continuously divide and differentiate into various tissues  Two Types:  Multipotent:
MH: 85 – 91, N:  In a single-celled organism, 1 cell is capable of every function needed to survive  In multicellular organisms, survival.
Genes and Development Chapter 16. Development All the changes that occur during an organism’s lifetime Cell specialization: Cell determination: specific.
12-9 and Turn In: Concept Map and Vocabs Warm up# 11-15
5-2a: Cloning How are mammals cloned?
Cloning and stem cells: facts and opinions A/Prof David Turner School of Medicine Flinders University
Reprogramming = Dedifferentiation - the process of converting somatic cell back in to pluripotent stems.
Stem Cell Research. Types of Stem Cells Embryonic Stem Cells – from embryos (fertilized egg cell) Embryonic Stem Cells – from embryos (fertilized egg.
Stem Cell Biology Presentors: Ayesha Bano, Allyn Bryan, and Caleb.
Stem Cells.
Stem Cells Untapped and unproven potential for treating human conditions Characteristics: capable of self renewal and differentiation Stem cell divides.
KOA Conference Eldoret 2016 Mutiso VM, Anzala O, Khainga SO, Otieno C, Ogalo JP, Bundi BN.
STEM CELLS: A Review.
 (1) recombinant DNA technology or DNA cloning,  (2) reproductive cloning  (3) therapeutic cloning.
Stem Cells.
Stem cell and regenerative medicine
What do we need to know to become stem cell literate?
Differentiation and Stem Cells
Stem Cells : Therapeutic Perspectives
Stem Cells & Cancer What? Where? How? Why?.
بسم الله الرحمن الرحيم.
Genes and Development CVHS Chapter 16.
Cancer as a genetic disease
Stem cells Chapter 7 Pages
BMI: Regenerative Medicine
Volume 11, Issue 6, Pages (December 2012)
Stem Cells and Cloning.
Reproductive cloning vs. Therapeutic cloning
Therapeutic vs. reproductive cloning
Plant and Animal Biotechnology
Ch. 15 Warm-Up Compare DNA methylation and histone acetylation.
Upgrading from iMac to iMicro
In the name of god.
Cell Differentiation (10.4)
Early Embryonic Development
terminally differentiated less tumorigenic/metastatic
M. William Lensch, Christine L. Mummery  Stem Cell Reports 
S. Tamir Rashid, Graeme J.M. Alexander  Journal of Hepatology 
Sec Notes Cell Cycle Continued.
Hank describes Stem Cells
Plant and Animal Biotechnology
Challenges to Biomedical Research- Cloning
Presentation transcript:

Embryology Doc. MUDr. Ing. RNDr. Peter Celec, DrSc., MPH

Stem cells Totipotency All tissue types Pluripotency All tissues except placenta and amniotic sac Multipotency Several related tissue types

Differentiation

Programming and reprogramming

Nucleus transfer John Bertrand Gurdon ( ) Nobel prize in Physiology or medicine 2012

Somatic cell nuclear transfer Dolly (5 July 1996 – 14 February 2003)

Cloning Reproductive Therapeutic

Cloning

Pluripotency

iPSC Shinya Yamanaka Kyoto University

iPS Reprogramming of differentiated cells Pluripotency No immune response Without retroviral vectors Without oncogenes pH? Reproducibility

Shinya Yamanaka (1962 – ) Nobel prize 2012 – Physiology or medicine

Malignant transformation Robert Weinberg ( ) Oncogenes Ras Tumor suppressors Rb1

Hallmarks of cancer Hanahan & Weinberg, Cell, 2000

Hallmarks of cancer Hanahan & Weinberg, Cell, 2011

Malignant transformation Bert Vogelstein (1949- ) Vogelgram

Genometastasis

Feedback: Privacy Policy Feedback
Do Not Sell My Personal Information
About project: SlidePlayer Terms of Service

© 2025 SlidePlayer.com. Inc. All rights reserved.