“CURRENT VIEW AND FUTURE DIRECTIONS ” Alzheimer’s disease Therapy Initiative (ADTI)

Slides:



Advertisements
Similar presentations
Ethics review and oversight for better governance of health research Amar Jesani Indian Journal of Medical Ethics Centre for Studies in Ethics and Rights.
Advertisements

Great Ormond Street Hospital for Children NHS Trust The School of Pharmacy UCL INSTITUTE OF CHILD HEALTH Centre for Paediatric Pharmacy Research Drug Development.
Trends in the Use of Evidence-Based Treatments for Coronary Artery Disease Among Women and the Elderly Findings From the Get With the Guidelines Quality-
Temporal Trends in the Prevalence of Diabetic Kidney Disease in the United States Ian H. de Boer, MD, MS, Tessa C. Rue, MS, Yoshio N. Hall, MD, Patrick.
Module 3 Brief Intervention. 3-2 Hhhh ADVISE APPROPRIATE ACTION FOLLOW UP - Supportive Care ASSESS Academic Social Behavioral Medical ASK Quantity/Frequency.
Edward P. Sloan, MD, MPH ACEP Clinical Policy Clinical Policy: Critical Issues in the Management of Adult Patients Presenting to the Emergency Department.
Health Line of Business Revised Health Domains January 26, 2005 Outcomes / Domains have been revised.
Selection of Data Sources for Observational Comparative Effectiveness Research Prepared for: Agency for Healthcare Research and Quality (AHRQ)
QUALITY OF LIFE ASSESSMENT IN PEOPLE LIVING WITH HIV/AIDS Antonieta Medina Lara HIV/AIDS and STI Knowledge Programme Liverpool School of Tropical Medicine.
S D C R N Graham A Jackson Professor of Dementia Care Alzheimer Scotland Centre for Policy and Practice University West of Scotland.
Acute Ischemic Stroke Management: 2004 Emergency Medicine Perspectives.
Nursing Science and the Foundation of Knowledge
Research Design: The Progression of Study Designs that Address a Clinical Question.
Overview of operational research in MSF Myriam Henkens, MD, MPH International Medical Coordinator MSF London 1st of June, 2006.
Welcome!. T0 Basic and applied research T1 Translation to Humans T2 Translation to Patients T3 Translation to Practice T4 Translation to Communities.
Putting the Patient at the Center of Health Care Research Joe Selby, MD, MPH Executive Director, Patient-Centered Outcomes Research Institute The Conference.
A Benefit-Risk Model to Facilitate DMC-Sponsor Communication and Decision Making Andreas Sashegyi PhD ELI LILLY AND COMPANY 1.
Down syndrome and Alzheimer’s disease: A retrospective medical records review Erin Klonoski LEND Fellow MPH Candidate April 30 th, 2010.
Real-World Assessment of Clinical Outcomes in Lower-Risk Myelofibrosis Patients Receiving Treatment with Ruxolitinib Davis KL et al. Proc ASH 2014;Abstract.
Cholinesterase Inhibitors in a real-world coverage study Revised outline Introduction: measurement for drug policymakers and assessment tools for clinicians.
| > Alzheimer’s disease is fast becoming one the greatest medial challenges facing American’s today  6 th leading cause.
Documentation of Care Provided Patient’s care - who should do it? WHY DOCUMENT? When should it occur? Where should it be documented? How should it be documented?
Working with people living with dementia and other long term conditions Karin Tancock Professional Affairs Officer for Older People & Long Term Conditions.
Aging & Developmental Disability-Just the Basics.
Preventive Healthcare for Older Adults Framing the Issue.
Measuring and reporting outcomes for BTOP grants: the UW iSchool approach Samantha Becker Research Project Manager U.S. IMPACT Study 1UW iSchool evaluation.
Trends in utilization of services associated with introduction of drug coverage for Cholinesterase Inhibitors (ChEI) Malcolm Maclure, ScD, Professor Wendy.
Standardized Assessment: Issues and Opportunities Lisa R. Shugarman, Ph.D. Director of Policy Alzheimer’s Advisory Committee.
PTP 661 EVIDENCE ABOUT INTERVENTIONS CRITICALLY APPRAISE THE QUALITY AND APPLICABILITY OF AN INTERVENTION RESEARCH STUDY Min Huang, PT, PhD, NCS.
Southern Africa CSO Consultation on Trade and HIV/AIDs: Road to Hong Kong.
Is the conscientious explicit and judicious use of current best evidence in making decision about the care of the individual patient (Dr. David Sackett)
Medical Research and Clinical Trials Rels 300 / Nurs October 2015.
Chronic Conditions in the U.S.
Evaluation of Psychosocial Support Services for Adolescent and Young Adult Patients at Roswell Park Cancer Institute Allison Polakiewicz, MPA Project Proposal.
Question 1 Please identify and discuss the most important outcomes to study in both children and adults. Please consider: –Whether the choice of outcomes.
© University of South Wales Royal College of Speech and Language Therapists Outcomes Conference and Hub Launch Belfast, May 1, 2014 Running a tight ship:
Children’s Policy Conference Austin, TX February 24, ECI as best practice model for children 0-3 years with developmental delays / chronic identified.
Palliative Care with Older Adults Section 3: Policy Issues Related To Aging And Palliative Care Gunnar Almgren, PhD University of Washington, School of.
Benefits of Guideline Standards to Older Americans: a patient perspective IOM Committee on Standards for Developing Trustworthy Clinical Practice Guidelines.
Regulatory and Reimbursement Harmonization An Industry Perspective Adrian Griffin | April 2016.
Advancing Health Economics, Services, Policy and Ethics Collecting Real World Evidence: HTA’s perspective Dr. Kelvin Chan, MD FRCPC MSc (Clin Epi) MSc.
Dr. Sabine Brookman-May, MD, PhD Regional Therapeutic Area Expert Oncology (Europe, Middle East, Africa) - Janssen R&D Improving patients involvement in.
PRAGMATIC Study Designs: Elderly Cancer Trials
Continuous Improvement & Real World Evidence: A Public Payer’s Perspective Suzanne McGurn, Assistant Deputy Minister and Executive Officer Ontario Public.
Drug Utilization Review & Drug Utilization Evaluation: An Overview
Danielle Lavallee, PharmD, PhD Department of Surgery
Patient Focused Drug Development An FDA Perspective
University of Washington,
Bozeman Health Clinical Research
Clinical Trials in IBD.
MULTIMORBIDITY: THE MOST COMMON CHRONIC CONDITION
Positive Impacts of Developing Novel Endpoints Generated by Mobile Technology for Use in Clinical Trials* SPECIFIC BENEFITS   SHORT-TERM MEDIUM-TERM LONG-TERM.
Optimizing Patient Outcomes in IBD
WHO Clinical Classification of PH Complex Cases in PH.
Sign critical appraisal course: exercise 2
Observational Studies vs. Randomized Controlled Trials (RCT)
Student placements in private practice; the case for and against!
Nat. Rev. Nephrol. doi: /nrneph
Jennifer M. Croswell, Barnett S. Kramer  Journal of Hepatology 
IV-E Prevention Family First Implementation & Policy Work Group
First meeting of the CIOMS Working Group XI: Patient involvement in the development and safe use of medicines April 2018, Geneva Mary O’Hare,
Drug Utilization Review & Drug Utilization Evaluation: An Overview
Patient Involvement in the Development and Use of Safe Medicines Introductory Section – Concepts to Consider CIOMS XI WG Second Meeting October 23-24,
The Research Question Background: Question:
Module 5: Formulating Research Questions
Using Your EMR for More than Just Documenting
Secondary outcomes in pharmacological and behavioral treatment trials standardized or tailored to intervention type? Kevin M. Gray, M.D. Professor and.
MRD Analysis in Chronic Lymphocytic Leukemia
Regulatory Perspective of the Use of EHRs in RCTs
Student placements in private practice; the case for and against!
Presentation transcript:

“CURRENT VIEW AND FUTURE DIRECTIONS ” Alzheimer’s disease Therapy Initiative (ADTI)

ADTI Many things we know about conducting research with older adults have been reaffirmed – Explanations must be clear and provided in a manner that people find understandable – Caregivers often appreciate talking to someone about their situation Some areas have been challenging

ADTI Overall, positive effects of ChEI medications are suggested through our results Consistent with previous research Small effects, but clinical relevant Reflect “real” life utilization of these medications

Collection of Unique Data Information about trends in utilization are emerging Use of novel measures that capture dimensions of benefit not tapped in conventional measures Treatment outcomes beyond clinical trial duration

Future Directions and Opportunities ADTI program provides an opportunity to utilize what we have learned and how that may be translated into future coverage policy