Genetic Mutations Shar – Pei Dog
Shar-Pei
Objective Explore how genes cause phenotypes in Shar-Pei dogs.
Instructions: 1. Read the New York Times Article: Canine Genetic Wrinkle Has Potential for Humans by Sindya N Bhanoo 2. Copy and answer the questions on the next slide 3. Discussion, notes and conclusion
Questions 1. What are the two phenotypes? 2. What substance causes the wrinkles? 3. What gene causes that substance? 4. How would the frequent fever be connected genetically to the wrinkles? Hint: Part C, Can You Sort it Out? page What is the connection to humans?
Phenotype variations
Discuss photo Which dog will be most likely have the fever trait? Which dog will be least likely to have the fever trait?
Conclusion Describe the connection between the shar-pei dog’s genotype and phenotype.