Hepatitis D (Delta) Virus d antigen HBsAg RNA 19 19 19

Hepatitis D - Clinical Features Coinfection severe acute disease low risk of chronic infection Superinfection usually develop chronic HDV infection high risk of severe chronic liver disease 20 20 20

Hepatitis D Virus Modes of Transmission Percutanous exposures injecting drug use Permucosal exposures sex contact 21 21 21

Typical Serologic Course HBV - HDV Coinfection Typical Serologic Course Symptoms ALT Elevated anti-HBs Titer IgM anti-HDV HDV RNA HBsAg Total anti-HDV Time after Exposure 22 22 22

HBV - HDV Superinfection Typical Serologic Course Jaundice Symptoms Total anti-HDV ALT Titer HDV RNA HBsAg IgM anti-HDV Time after Exposure 23 23 23

Geographic Distribution of HDV Infection Taiwan Pacific Islands HDV Prevalence High Intermediate Low Very Low No Data 24 24 24

Hepatitis D - Prevention HBV-HDV Coinfection Pre or postexposure prophylaxis to prevent HBV infection HBV-HDV Superinfection Education to reduce risk behaviors among persons with chronic HBV infection 25 25 25